Skoulakis Charalampos, Chimona Theognosia S, Tsirevelou Paraskevi, Papadakis Chariton E
ENT Department, General Hospital of Volos, Greece.
Cases J. 2010 Feb 3;3:52. doi: 10.1186/1757-1626-3-52.
Leiomyosarcomas are rare tumors. The most common site for head and neck leiomyosarcomas is the oral cavity, followed by sinonasal tract and skin. Subcutaneous leiomyosarcomas are thought to arise from small to medium-sized blood vessels in the subcutaneous tissue.
A 67-year-old female patient underwent excision of a slow growing neck mass of the left posterior neck triangle after a thorough clinical and laboratory examination. The lesion was located in the subcutis and fine needle aspiration biopsy revealed malignant features. Histology revealed subcutaneous leiomyosarcoma and the patient is free from local recurrence and distant metastases 3 years after wide excision of the lesion.
The primary modality of therapy of subcutaneous leiomyosarcoma is surgery, adjuvant radiotherapy or chemotherapy may be used for control of local recurrence, in case of positive surgical margins, high-grade or large tumors.
平滑肌肉瘤是罕见肿瘤。头颈部平滑肌肉瘤最常见的部位是口腔,其次是鼻窦道和皮肤。皮下平滑肌肉瘤被认为起源于皮下组织的中小血管。
一名67岁女性患者在经过全面的临床和实验室检查后,接受了左侧后颈部三角区缓慢生长的颈部肿块切除术。病变位于皮下,细针穿刺活检显示有恶性特征。组织学检查显示为皮下平滑肌肉瘤,在广泛切除病变3年后,患者无局部复发和远处转移。
皮下平滑肌肉瘤的主要治疗方式是手术,对于手术切缘阳性、高级别或大肿瘤的情况,可使用辅助放疗或化疗来控制局部复发。