The Fifth Affiliated Hospital of Guangzhou Medical University, No.621, Gangwan Road, Huangpu District, Guangzhou City, Guangdong Province, China.
Dermatology Hospital of Southern Medical University, No. 2 Lujing Road, Yuexiu District, Guangzhou City, Guangdong Province, China.
Photodiagnosis Photodyn Ther. 2021 Dec;36:102468. doi: 10.1016/j.pdpdt.2021.102468. Epub 2021 Jul 29.
Keratoacanthoma centrifugum marginatum (KCM) of the skin is a rare variant of cutaneous keratoacantoma. KCM was first reported in 1962 andpresents with progressive peripheral expansion , no spontaneous clearing and a bank-shaped outer wall with concurrent central healing. Treatment options include topical and systemic therapies.Surgical intervention is the preferred therapy for solitary KCM. We report on surgery and photodynamic therapy delivered sequentially to treat a giant facial Keratoacanthoma centrifugum marginatum patient. It was safe and effective .
皮肤离心性环状角化棘皮瘤(KCM)是一种罕见的皮肤角化棘皮瘤变异型。KCM 于 1962 年首次报道,表现为进行性外周扩展,无自发消退,呈堤状外壁伴同时性中央愈合。治疗选择包括局部和全身治疗。手术干预是治疗孤立性 KCM 的首选方法。我们报告了一例巨大面部离心性环状角化棘皮瘤患者先后接受手术和光动力疗法治疗的情况,该方法安全有效。