新型副粘病毒引起的脑膜脑炎：一种新发疾病的高级MRI病例报告

Meningoencephalitis caused by a novel paramyxovirus: an advanced MRI case report in an emerging disease.

作者信息

Lim C C, Sitoh Y Y, Lee K E, Kurup A, Hui F

机构信息

Department of Diagnostic Imaging, Tan Tock Seng Hospital, Singapore.

出版信息

Singapore Med J. 1999 May;40(5):356-8.

PMID:10489496

Abstract

Eleven abattoir workers in Singapore were infected in March 1999 by an outbreak caused by the Nipah virus. This newly discovered, Hendra-like paramyxovirus causes acute infection of the CNS. We present the magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (MRS) findings in a patient suffering from acute meningoencephalitis. Multiple small white matter lesions were detected on diffusion-weighted imaging (DWI) and T2-weighted images. There were no abnormalities detected on MRS. We believe this to be the first reported MRI findings in this novel zoonotic viral disease.

摘要

1999年3月，新加坡11名屠宰场工人因尼帕病毒爆发而感染。这种新发现的、类似亨德拉病毒的副粘病毒会引发中枢神经系统的急性感染。我们展示了一名患有急性脑膜脑炎患者的磁共振成像（MRI）和质子磁共振波谱（MRS）检查结果。在扩散加权成像（DWI）和T2加权图像上检测到多个小的白质病变。MRS未检测到异常。我们认为这是这种新型人畜共患病毒性疾病首次报告的MRI检查结果。