新型隐球菌在鸽粪中发生黑化的证据：对发病机制的启示。
Evidence that Cryptococcus neoformans is melanized in pigeon excreta: implications for pathogenesis.
作者信息
Nosanchuk J D, Rudolph J, Rosas A L, Casadevall A
机构信息
Department of Medicine (Division of Infectious Diseases), Albert Einstein College of Medicine, Bronx, New York 10461, USA.
出版信息
Infect Immun. 1999 Oct;67(10):5477-9. doi: 10.1128/IAI.67.10.5477-5479.1999.
Abstract
Structures similar to the melanin "ghosts" of melanized cryptococcal cells were isolated from pigeon excreta contaminated with Cryptococcus neoformans, and their growth in pigeon excreta supported melanization. The results suggest that environmental C. neoformans cells are melanized and imply that initial infection may involve exposure to melanized cells.
摘要
从被新型隐球菌污染的鸽子粪便中分离出了与黑色素化隐球菌细胞的黑色素“幽灵”相似的结构，并且它们在鸽子粪便中的生长促进了黑色素的形成。这些结果表明环境中的新型隐球菌细胞会发生黑色素化，这意味着初始感染可能涉及接触黑色素化细胞。
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