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氧化应激介导氧化型低密度脂蛋白和氧化型脂蛋白(a)诱导的细胞凋亡。

Oxidative stress mediates apoptosis induced by oxidized low-density lipoprotein and oxidized lipoprotein(a).

作者信息

Heermeier K, Schneider R, Heinloth A, Wanner C, Dimmeler S, Galle J

机构信息

Department of Medicine, Division of Nephrology, University Hospital of Würzburg, Germany.

出版信息

Kidney Int. 1999 Oct;56(4):1310-2. doi: 10.1046/j.1523-1755.1999.00685.x.

DOI:10.1046/j.1523-1755.1999.00685.x
PMID:10504482
Abstract

We measured oxidative stress caused by lipoproteins in human umbilical vein endothelial cells and rabbit aorta. Oxidized lipoprotein(a) was the more potent stimulus over oxidized low density lipoprotein, and we believe that both influence the pathogenesis of atherosclerosis.

摘要

我们测定了人脐静脉内皮细胞和兔主动脉中脂蛋白引起的氧化应激。氧化型脂蛋白（a）比氧化型低密度脂蛋白的刺激作用更强，并且我们认为二者均影响动脉粥样硬化的发病机制。

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