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人类免疫缺陷病毒1型(HIV-1)感染者及艾滋病患者的耳科手术

Otologic surgery in patients with HIV-1 and AIDS.

作者信息

Kohan D, Giacchi R J

机构信息

Department of Otolaryngology, New York University School of Medicine.

出版信息

Otolaryngol Head Neck Surg. 1999 Oct;121(4):355-60. doi: 10.1016/S0194-5998(99)70220-2.

Abstract

Otologic disease in patients infected with HIV occurs frequently and usually represents rhinologic disease and associated eustachian tube dysfunction rather than manifestations of HIV infection. As in all patients, the decision to operate on an HIV-infected individual who would benefit from major otologic surgery is a balance between the risks of the procedure and the possible benefits to the patient. Many concerns regarding wound infection and healing have been raised. The objective of this study is to evaluate the outcome of otologic procedures in this population. The charts of 9 men and 4 women were reviewed. Seven patients (54%) met the Centers for Disease Control and Prevention criteria for AIDS. Patients with chronic otitis media (46%) underwent tympanomastoidectomies, and the cases of acute mastoiditis (31%) were managed with simple mastoidectomies. Other procedures included repair of cerebrospinal fluid leak (15%) and stapedectomy (8%). Two patients had early complications and died during their hospitalizations. Three patients had prolonged hospital courses requiring long-term antibiotics. These 5 patients underwent urgent procedures and were severely immunocompromised. Of the remaining 8 patients only 2 had AIDS, and all had an uncomplicated postoperative course. Six of these patients were followed up for more than 1 year, and only 2 developed subsequent otologic disease.

摘要

感染HIV的患者常发生耳科疾病,通常表现为鼻科疾病及相关的咽鼓管功能障碍,而非HIV感染的表现。与所有患者一样,对于能从大型耳科手术中获益的HIV感染个体,决定是否进行手术需在手术风险和对患者可能的益处之间取得平衡。人们对伤口感染和愈合提出了许多担忧。本研究的目的是评估该人群中耳科手术的结果。回顾了9名男性和4名女性的病历。7名患者(54%)符合美国疾病控制与预防中心的艾滋病标准。慢性中耳炎患者(46%)接受了鼓室乳突切除术,急性乳突炎病例(31%)采用单纯乳突切除术治疗。其他手术包括脑脊液漏修补术(15%)和镫骨切除术(8%)。2名患者出现早期并发症并在住院期间死亡。3名患者住院时间延长,需要长期使用抗生素。这5名患者接受了急诊手术,免疫功能严重受损。其余8名患者中只有2名患有艾滋病,所有患者术后过程均无并发症。其中6名患者随访超过1年,只有2名随后出现耳科疾病。

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