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磁共振成像造影剂的安全性。

Safety of magnetic resonance imaging contrast agents.

作者信息

Shellock F G, Kanal E

机构信息

University of Southern California School of Medicine and Shellock R & D Services, Inc., Los Angeles, California 90045, USA.

出版信息

J Magn Reson Imaging. 1999 Sep;10(3):477-84. doi: 10.1002/(sici)1522-2586(199909)10:3<477::aid-jmri33>3.0.co;2-e.

Abstract

Many of the MR examinations performed in the world each year are accompanied by administration of one of these frequently used intravenous contrast agents: Magnevist, Omniscan, and ProHance. Accordingly, MR practitioners must understand the basic pharmacokinetics, side effects, and the potential for adverse events for these contrast agents. Additionally, MR practitioners must know how to manage side effects and adverse events that may occur in association with the administration of contrast agents. Notably, the use of MR imaging contrast agents in special patient populations must be understood. This article discusses each of these important issues.

摘要

每年在全球范围内进行的许多磁共振成像(MR)检查都伴随着使用这些常用静脉造影剂中的一种:钆喷酸葡胺(马根维显)、钆双胺(欧乃影)和钆贝葡胺(普美显)。因此,从事MR检查的医务人员必须了解这些造影剂的基本药代动力学、副作用以及发生不良事件的可能性。此外,医务人员必须知道如何处理与造影剂使用相关的副作用和不良事件。值得注意的是,必须了解在特殊患者群体中使用MR成像造影剂的情况。本文将讨论这些重要问题。

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