Troyanovsky S M
Division of Dermatology Washington University Medical School Campus Box 8123, 660 South Euclid Avenue, St. Louis, MO 63110, USA.
Curr Opin Cell Biol. 1999 Oct;11(5):561-6. doi: 10.1016/s0955-0674(99)00021-6.
Cell-cell adhesion complexes play an important role in the organization and behavior of cells in tissues. An important step in the formation of such complexes is the clustering of the adhesion receptors; this is critical for proper adhesion, for anchorage of the cytoskeleton to the plasma membrane, and for generation of different intracellular signals. Recent advances reveal that several interconnected mechanisms are responsible for clustering of the different adhesion receptors.
细胞间粘附复合体在组织中细胞的组织和行为方面发挥着重要作用。形成此类复合体的一个重要步骤是粘附受体的聚集；这对于适当的粘附、细胞骨架与质膜的锚定以及不同细胞内信号的产生至关重要。最近的进展表明，几种相互关联的机制负责不同粘附受体的聚集。
