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南非德班中南部哮喘和呼吸道症状的患病率

Prevalence of asthma and respiratory symptoms in south-central Durban, South Africa.

作者信息

Nriagu J, Robins T, Gary L, Liggans G, Davila R, Supuwood K, Harvey C, Jinabhai C C, Naidoo R

机构信息

Department of Environmental & Industrial Health, School of Public Health, University of Michigan, Ann Arbor 48109, USA.

出版信息

Eur J Epidemiol. 1999 Sep;15(8):747-55. doi: 10.1023/a:1007653709188.

Abstract

The prevalence of asthma and respiratory symptoms in south-central Durban, one of the most heavily polluted areas of South Africa, has been determined using a cross-sectional survey of 213 households in the communities of Merewent (97% Indians) and Austerville (98% coloreds). The study population consisted of 367 children (less than 17 years old) and 693 adults. About 10% of the children and 12% of adults reported doctor diagnosed asthma. The self-reported prevalence rates for wheezing (3740%) and attacks of shortness of breath with wheeze (16-28%) were much higher than that for doctor diagnosed asthma and common co-occurrence of the three symptoms is found. The prevalence rates for other respiratory symptoms include 33-35% for chronic cough, 31-32% for chronic phlegm, 44-50% for frequent blocked-runny nose, and 16-27% for sinusitis. Factors in the community that were associated with asthma, wheeze and shortness of breath with wheeze among the adult population included cigarette smoking, use of insecticides (coils and pump spray) and home ownership. An association between asthma among children and a number of household risk factors including dampness, carpet, pets or use of pesticides was not apparent in the community. Asthma prevalence was strongly correlated with missing of school by children (odds ratio (OR): 44; 95% confidence interval (CI): 13-141). The study serves to draw attention to a growing but neglected public health problem in urban areas of Africa.

摘要

德班中南部是南非污染最严重的地区之一,通过对梅勒温特(97%为印度人)和奥斯特维尔(98%为有色人种)社区的213户家庭进行横断面调查,确定了该地区哮喘和呼吸道症状的患病率。研究人群包括367名儿童(17岁以下)和693名成年人。约10%的儿童和12%的成年人报告医生诊断为哮喘。自我报告的喘息患病率(37%-40%)和伴有喘息的呼吸急促发作患病率(16%-28%)远高于医生诊断的哮喘患病率,且发现这三种症状常同时出现。其他呼吸道症状的患病率包括慢性咳嗽33%-35%、慢性咳痰31%-32%、频繁鼻塞流涕44%-50%以及鼻窦炎16%-27%。在成年人群中,与哮喘、喘息和伴有喘息的呼吸急促相关的社区因素包括吸烟、使用杀虫剂(蚊香和喷雾器)以及拥有自有住房。在该社区中,儿童哮喘与一些家庭危险因素(包括潮湿、地毯、宠物或使用杀虫剂)之间的关联并不明显。哮喘患病率与儿童缺课情况密切相关(优势比(OR):4.4;95%置信区间(CI):1.3-14.1)。该研究旨在引起人们对非洲城市地区一个日益严重但被忽视的公共卫生问题的关注。

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