Maier W C, Arrighi H M, Morray B, Llewellyn C, Redding G J
University of North Carolina, Chapel Hill 27514, USA.
Environ Health Perspect. 1997 Feb;105(2):208-14. doi: 10.1289/ehp.97105208.
Indoor risk factors for physician-diagnosed asthma and wheezing in the past 12 months without previous asthma diagnosis were assessed in a survey of parents of 5-9-year-old Seattle primary school students. Among the 925 respondents, 106 (11%) reported a physician diagnosis of asthma, 66 (7%) had wheezing without diagnosis, and 753 (82%) were asymptomatic. After adjusting for age, sex, gender, ethnicity, medical history, socioeconomic status (SES) and parental asthma status, an increased risk of physician diagnosis of asthma was associated with household water damage, the presence of one or more household tobacco smokers, and at least occasional environmental tobacco smoke (ETS) exposure. Similarly, an increased risk of wheezing in the past 12 months among children without diagnosed asthma was associated with household water damage, presence of one or more household tobacco smokers, and occasional or more frequent ETS exposure. No increased risk of either condition was associated with gas, wood, or kerosene stove use, household mold, basement water, or wall/window dampness. Similarities in the indoor risk factors patterns between diagnosed asthma and wheezing without diagnosis suggested a similar etiology of these two conditions. The slightly higher association between ETS and asthma may indicate that parents of diagnosed asthmatics were more conscious of ETS, and were more likely to prohibit household smoking by resident smokers. Future research is needed to quantify which aspects of household water damage are related to respiratory illness.
在一项针对西雅图5至9岁小学生家长的调查中,评估了过去12个月内经医生诊断为哮喘和喘息但此前未被诊断为哮喘的室内风险因素。在925名受访者中,106人(11%)报告经医生诊断患有哮喘,66人(7%)有未确诊的喘息症状,753人(82%)无症状。在对年龄、性别、种族、病史、社会经济地位(SES)和父母哮喘状况进行调整后,经医生诊断为哮喘的风险增加与家庭水损、家中有一名或多名吸烟者以及至少偶尔接触环境烟草烟雾(ETS)有关。同样,在未确诊哮喘的儿童中,过去12个月内喘息风险增加与家庭水损、家中有一名或多名吸烟者以及偶尔或更频繁接触ETS有关。这两种情况的风险增加均与使用燃气、木材或煤油炉、家庭霉菌、地下室积水或墙壁/窗户潮湿无关。已确诊哮喘和未确诊喘息的室内风险因素模式相似,表明这两种情况的病因相似。ETS与哮喘之间略高的关联可能表明,已确诊哮喘儿童的家长对ETS更为关注,并且更有可能禁止家中吸烟者吸烟。需要进一步的研究来量化家庭水损的哪些方面与呼吸道疾病有关。