Kues H A, D'Anna S A, Osiander R, Green W R, Monahan J C
The Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland, USA.
Bioelectromagnetics. 1999 Dec;20(8):463-73.
This study was designed to examine ocular effects associated with exposure to millimeter waves (60 GHz). Rabbits served as the primary experimental subjects. To confirm the results of the rabbit experiments in a higher species, the second phase of the study used nonhuman primates (Macaca mulatta). First, this study used time-resolved infrared radiometry to assess the field distribution patterns produced by different antennas operating at 60 GHz. These results allowed us to select an antenna that produced a uniform energy distribution and the best distance at which to expose our experimental subjects. The study then examined ocular changes after exposure at an incident power density of 10 mW/cm(2). Acute exposure of both rabbits and nonhuman primates consisted of a single 8 h exposure, and the repeated exposure protocol consisted of five separate 4 h exposures on consecutive days. One eye in each animal was exposed and the contralateral eye served as the sham-exposed control. After postexposure diagnostic examinations, animals were euthanized and the eyes were removed. Ocular tissue was examined by both light and transmission electron microscopy. Neither microscopic examinations nor the diagnostic procedures performed on the eyes of acute and repeatedly exposed rabbits found any ocular changes that could be attributed to millimeter-wave exposure at 10 mW/cm(2). Examination of the primates after comparable exposures also failed to detect any ocular changes due to exposure. On the basis of our results, we conclude that single or repeated exposure to 60 GHz CW radiation at 10 mW/cm(2) does not result in any detectable ocular damage.
本研究旨在检测与暴露于毫米波(60吉赫兹)相关的眼部效应。兔子作为主要实验对象。为了在更高等物种中证实兔子实验的结果,研究的第二阶段使用了非人灵长类动物(恒河猴)。首先,本研究使用时间分辨红外辐射测量法来评估由工作在60吉赫兹的不同天线产生的场分布模式。这些结果使我们能够选择一个能产生均匀能量分布的天线以及用于暴露实验对象的最佳距离。然后研究在入射功率密度为10毫瓦/平方厘米的情况下暴露后的眼部变化。兔子和非人灵长类动物的急性暴露均为单次8小时暴露,重复暴露方案为连续五天进行五次单独的4小时暴露。每只动物的一只眼睛接受暴露,对侧眼睛作为假暴露对照。暴露后进行诊断检查后,对动物实施安乐死并摘除眼睛。通过光学显微镜和透射电子显微镜检查眼部组织。对急性暴露和重复暴露的兔子眼睛进行的显微镜检查和诊断程序均未发现任何可归因于10毫瓦/平方厘米毫米波暴露的眼部变化。对类似暴露后的灵长类动物进行检查也未能检测到因暴露引起的任何眼部变化。基于我们的结果,我们得出结论,以10毫瓦/平方厘米的功率单次或重复暴露于60吉赫兹连续波辐射不会导致任何可检测到的眼部损伤。