Banks M, Torraca L S, Greenwood A G, Taylor D C
Veterinary Laboratories Agency, New Haw, Addlestone, Surrey.
Vet Rec. 1999 Sep 25;145(13):362-5. doi: 10.1136/vr.145.13.362.
Five of eight bears died during an outbreak of Aujeszky's disease in a travelling circus in the north of Spain. The bears had been fed on a diet which included raw pigs' heads. One of three Himalayan bears and a Kodiak bear died acutely with signs of the disease. One of four polar bears died acutely without signs, another died with signs of Aujeszky's disease while it was being treated, and a third died with enteritis and disseminated intestinal coagulation some time later without showing signs of the disease. A fourth polar bear recovered from the same gastrointestinal problem without showing signs of the disease. Although one of the two surviving Himalayan bears showed some signs referrable to Aujeszky's disease, the results of tests for neutralising antibodies were negative. Two of the polar bears, the Himalayan bear and the Kodiak bear were examined postmortem and three of them were examined histologically. No lesions referable to Aujeszky's disease were found. The tissues from one female polar bear were examined and shown to be positive for Aujeszky's disease virus by virus isolation, polymerase chain reaction, electron microscopy and fluorescent antibody tests. The DNA of the isolate was shown to be similar to that of the strains of the virus circulating in pigs in northern Spain some years earlier.
在西班牙北部一个巡回马戏团爆发奥耶斯基氏病期间，八只熊中有五只死亡。这些熊的饮食包括生猪头。三只喜马拉雅熊和一只科迪亚克熊中有一只急性死亡，表现出该病的症状。四只北极熊中有一只急性死亡，无明显症状，另一只在接受治疗时死于奥耶斯基氏病，第三只在一段时间后死于肠炎和弥散性肠内凝血，未表现出该病症状。第四只北极熊从相同的胃肠道问题中康复，未表现出该病症状。尽管两只幸存的喜马拉雅熊中有一只表现出一些可归因于奥耶斯基氏病的症状，但中和抗体检测结果为阴性。对两只北极熊、喜马拉雅熊和科迪亚克熊中的三只进行了尸检，其中三只进行了组织学检查。未发现可归因于奥耶斯基氏病的病变。对一只雌性北极熊的组织进行了检查，通过病毒分离、聚合酶链反应、电子显微镜和荧光抗体检测，显示其对奥耶斯基氏病病毒呈阳性。分离出的病毒DNA显示与几年前在西班牙北部猪群中传播的病毒株相似。
