蜂胶和蜂毒对某些直接和间接作用诱变剂致突变性的抑制作用。
Inhibitory effect of propolis and bee venom on the mutagenicity of some direct- and indirect-acting mutagens.
作者信息
Varanda E A, Monti R, Tavares D C
机构信息
Department of Biological Sciences-Faculty of Pharmaceutical Sciences of Araraquara, Estadual Paulist University, São Paulo, Brazil.
出版信息
Teratog Carcinog Mutagen. 1999;19(6):403-13.
The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybee (Apis mellifera) venom, both collected in the State of São Paulo, Brazil, was assessed by the Salmonella/microsome assay upon direct- and indirect-acting mutagens. EEP had inhibitory effect (in an ascending order) on the mutagenicity power of daunomycin (TA102), benzo(a)pyrene (TA100), and aflatoxin B(1)(TA98) and the venom acted against the mutagenicity of 4-nitro-o-phenylenediamine (TA98) and daunomycin (TA102). Teratogenesis Carcinog. Mutagen. 19:403-413, 1999.
通过沙门氏菌/微粒体试验，对直接和间接作用的诱变剂，评估了巴西圣保罗州采集的蜂胶乙醇提取物（EEP）和蜜蜂（意大利蜜蜂）毒液的抗诱变作用。EEP对柔红霉素（TA102）、苯并(a)芘（TA100）和黄曲霉毒素B(1)（TA98）的诱变性具有抑制作用（呈升序），毒液则对4-硝基邻苯二胺（TA98）和柔红霉素（TA102）的诱变性有对抗作用。《致畸学、致癌学、诱变学》1999年第19卷，第403 - 413页。
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