Baker W K
Proc Natl Acad Sci U S A. 1975 Oct;72(10):4095-9. doi: 10.1073/pnas.72.10.4095.
The previously described allelic frequencies and linkage disequilibrium among the active and null alleles of four tightly linked loci coding for the alpha-esterases were found to be maintained by one population for 5 years, and were found to be present in two other populations which were shown to be genetically distinct from the first. It appears that enzyme variants coded by these highly polymorphic loci are being maintained in the populations by selective forces.
编码α - 酯酶的四个紧密连锁基因座的活性和无效等位基因之间，先前描述的等位基因频率和连锁不平衡现象，被发现一个群体维持了5年，并且在另外两个与第一个群体遗传上不同的群体中也存在。看来由这些高度多态性基因座编码的酶变体正通过选择力在群体中得以维持。
