Pallasaho P, Lundbäck B, Läspä S L, Jönsson E, Kotaniemi J, Sovijärvi A R, Laitinen L A
Department of Medicine, Helsinki University Central Hospital, Finland.
Respir Med. 1999 Nov;93(11):798-809. doi: 10.1016/s0954-6111(99)90265-2.
To assess the prevalence of asthma, chronic bronchitis and respiratory symptoms, and to calculate risk factors for them, we performed a postal survey in Helsinki, the capital of Finland. During the spring of 1996, questionnaires were mailed to a random sample of 8000 individuals aged 20-69. The total response rate was 76%, with 6062 complete answers. The prevalence of having ever had asthma was 7.2%, physician-diagnosed asthma was 6.6% and physician-diagnosed chronic bronchitis was 3.7%. Asthma was significantly more common among women than men, but no gender differences existed in prevalence of chronic bronchitis. The most common respiratory symptom was sputum production when coughing, reported by 27%. During the previous 12 months, wheezing had occurred in 20% and attacks of shortness of breath in 13% of subjects. Generally, the prevalence of different respiratory symptoms were significantly higher among smokers. The most important risk factor for asthma was a family history of asthma (Odds ratio:OR 3.3). Multivariate analysis revealed that being a member of the socioeconomic group, manual workers, was associated with a significantly increased risk for chronic productive cough (OR 1.7), and for wheezing during the previous 12 months (OR 1.7). Manual workers of both genders had the highest prevalence of asthma, chronic productive cough and wheezing during the previous 12 months. The prevalence of asthma in Helsinki was higher than previously found in Finland, and was at a similar level to that of other Nordic countries. In contrast, prevalence of chronic bronchitis was lower than previously shown in Finland.
为评估哮喘、慢性支气管炎及呼吸道症状的患病率,并计算其风险因素,我们在芬兰首都赫尔辛基开展了一项邮寄调查。1996年春季,我们向8000名年龄在20至69岁的个体随机样本邮寄了调查问卷。总回复率为76%,共收到6062份完整答案。曾患哮喘的患病率为7.2%,医生诊断的哮喘患病率为6.6%,医生诊断的慢性支气管炎患病率为3.7%。哮喘在女性中比男性更为常见,但慢性支气管炎的患病率不存在性别差异。最常见的呼吸道症状是咳嗽时有痰,有27%的人报告有此症状。在之前的12个月里,20%的受试者出现过喘息,13%的受试者出现过呼吸急促发作。一般来说,吸烟者中不同呼吸道症状的患病率明显更高。哮喘最重要的风险因素是哮喘家族史(优势比:OR 3.3)。多变量分析显示,作为社会经济群体中的体力劳动者,患慢性咳痰(OR 1.7)及在之前12个月内喘息(OR 1.7)的风险显著增加。在之前12个月里,男女体力劳动者的哮喘、慢性咳痰和喘息患病率最高。赫尔辛基的哮喘患病率高于芬兰此前的调查结果,与其他北欧国家的水平相近。相比之下,慢性支气管炎的患病率低于芬兰此前的调查结果。