Kotaniemi Jyrki-Tapani, Pallasaho Paula, Sovijärvi Anssi R A, Laitinen Lauri A, Lundbäck Bo
Department of Pulmonary Medicine, Länsi-Pohja Central Hospital, Kemi, Finland.
J Asthma. 2002 Oct;39(7):649-58. doi: 10.1081/jas-120014930.
We have compared data from northern and southern Finland in a large epidemiological survey on respiratory conditions. The aim was to compare the prevalence of respiratory symptoms, asthma, and chronic bronchitis in northern and southern Finland. The study was a part of comparative studies in Finland, Estonia, and Sweden, the FinEsS studies. Data from a postal survey on subjects aged 20-69 was analyzed. Participation rate was 84% of 7937 invited in Lapland in the north, and 77% of 7877 in Helsinki in the south. Physician-diagnosed asthma was reported by 5.6% in Helsinki, and by 5.5% in Lapland. Symptoms common in asthma were also equally prevalent in the two areas. Hay fever was significantly more common in Helsinki, 36% vs. 26% (p < 0.001). The prevalence for physician-diagnosed chronic bronchitis was not significantly higher in Helsinki (3.4%) than in Lapland (2.9%). Those working outdoors reported more bronchitic symptoms than people working indoors (p < 0.05). Respiratory symptoms provoked by pollen or animal dander were more common in Helsinki, while symptoms provoked by inhaled irritants or cold weather conditions were more prevalent in Lapland. Current smoking was equally prevalent: 37% in Lapland and 38% in Helsinki. Risk factor analysis showed an elevated risk for chronic productive cough for living in Helsinki (OR 1.32), however, increasing age and current smoking were the strongest risk factors. In conclusion, prevalence of asthma and asthma-related symptoms was similar in southern and northern Finland, but chronic bronchitis and bronchitic symptoms were more common in Helsinki, and the highest prevalence was found among current smokers working outdoors. Respiratory symptoms in cold weather were more prevalent in the north, while hay fever and respiratory symptoms provoked by allergens were more common in the south. The results support the view that environmental factors have a substantial effect on respiratory symptoms, but less effect on the prevalence of asthma.
在一项关于呼吸道疾病的大型流行病学调查中,我们比较了芬兰北部和南部的数据。目的是比较芬兰北部和南部呼吸道症状、哮喘和慢性支气管炎的患病率。该研究是芬兰、爱沙尼亚和瑞典比较研究(FinEsS研究)的一部分。对20 - 69岁人群的邮政调查数据进行了分析。北部拉普兰地区7937名受邀者的参与率为84%,南部赫尔辛基地区7877名受邀者的参与率为77%。赫尔辛基有5.6%的人报告经医生诊断患有哮喘,拉普兰为5.5%。哮喘常见症状在两个地区的患病率也相同。花粉症在赫尔辛基明显更常见,分别为36%和26%(p < 0.001)。经医生诊断的慢性支气管炎患病率在赫尔辛基(3.4%)并不显著高于拉普兰(2.9%)。从事户外工作的人报告的支气管炎症状比室内工作的人更多(p < 0.05)。花粉或动物皮屑引发的呼吸道症状在赫尔辛基更常见,而吸入性刺激物或寒冷天气引发的症状在拉普兰更普遍。当前吸烟率相同:拉普兰为37%,赫尔辛基为38%。危险因素分析显示,居住在赫尔辛基患慢性咳痰咳嗽的风险升高(比值比1.32),然而,年龄增长和当前吸烟是最强的危险因素。总之,芬兰南部和北部哮喘及哮喘相关症状的患病率相似,但慢性支气管炎和支气管炎症状在赫尔辛基更常见,且患病率最高的是从事户外工作的当前吸烟者。寒冷天气下的呼吸道症状在北部更普遍,而花粉症和过敏原引发的呼吸道症状在南部更常见。结果支持以下观点:环境因素对呼吸道症状有重大影响,但对哮喘患病率的影响较小。