Sprangers M A
Department of Medical Psychology, Academic Medical Center, University of Amsterdam, The Netherlands.
Semin Oncol. 1999 Dec;26(6):691-6.
There is increasing recognition of the need to assess the impact of colorectal cancer and its treatment on patients' quality of life (QL). An overview is provided of generic and (colorectal) cancer-specific QL questionnaires that yield adequate levels of reliability and validity. These measures have been or could be used in clinical research settings among colorectal cancer patients. Additionally, QL-based studies in colorectal cancer aimed at identifying the most optimal (cost-) effective treatment, or the parameters that best predict objective outcome, are described and exemplified. As is illustrated, QL data complement clinical outcomes and are essential to further improve the treatment and care of colorectal cancer patients and to support decision-making.
人们越来越认识到评估结直肠癌及其治疗对患者生活质量（QL）的影响的必要性。本文概述了具有足够可靠性和有效性水平的通用及（结直肠癌）特定癌症的QL问卷。这些测量方法已经或可用于结直肠癌患者的临床研究环境中。此外，还描述并举例说明了旨在确定最优化（成本）效益治疗或最能预测客观结果的参数的结直肠癌基于QL的研究。如图所示，QL数据补充了临床结果，对于进一步改善结直肠癌患者的治疗和护理以及支持决策至关重要。
