Jones K, Cleary R, Hyland M
University of Newcastle.
Br J Gen Pract. 1999 Jan;49(438):23-6.
There is a need in primary care for simple asthma outcome measures that are valid in terms of their relationship with lung function and capable of predicting those patients for whom additional management is indicated.
To assess the predictive validity of a revised asthma morbidity index in United Kingdom (UK) general practice.
Morbidity index and peak flow rate data were gathered from nine general practices over a three-month period. Two postal questionnaire surveys, one year apart, were conducted in one Tyneside general practice. Morbidity index data from 570 asthmatic patients were gathered in the first survey and used to predict morbidity over the next year.
For 120 responders with low morbidity, mean peak flow as a percentage of the predicted value was 91% (SD = 21%); for 91 responders with medium morbidity, the percentage was 77% (SD = 21%); and for 90 responders with high morbidity, it was 63% (SD = 29%). Fifty-seven per cent of the morbidity index categories remained unchanged after 12 months. The relative risks of high morbidity for having any acute asthma attacks, more than four attacks, and needing oral steroids during a one year period were 2.88 (CI = 1.87 to 4.43), 2.52 (CI = 1.84 to 3.44) and 2.38 (CI = 1.70 to 3.33) respectively.
The revised morbidity index is a simple and valid tool for the opportunistic surveillance of asthma in primary care.
基层医疗需要简单的哮喘结局指标,这些指标在与肺功能的关系方面是有效的,并且能够预测哪些患者需要额外的治疗。
评估修订后的哮喘发病率指数在英国全科医疗中的预测效度。
在三个月的时间里,从九个全科医疗诊所收集发病率指数和峰值流速数据。在泰恩赛德的一个全科医疗诊所进行了两次间隔一年的邮寄问卷调查。在第一次调查中收集了570名哮喘患者的发病率指数数据,并用于预测下一年的发病率。
对于120名低发病率的应答者,平均峰值流速占预测值的百分比为91%(标准差=21%);对于91名中等发病率的应答者,该百分比为77%(标准差=21%);对于90名高发病率的应答者,为63%(标准差=29%)。12个月后,57%的发病率指数类别保持不变。在一年期间发生任何急性哮喘发作、发作超过四次以及需要口服类固醇的高发病率的相对风险分别为2.88(可信区间=1.87至4.43)、2.52(可信区间=1.84至3.44)和2.38(可信区间=1.70至3.33)。
修订后的发病率指数是基层医疗中哮喘机会性监测的一种简单有效的工具。