Metabolism of a prototype mycotoxin, aflatoxin B1, and its genetic regulation.
作者信息
Gurtoo H L, Dahms R, Vaught J B
出版信息
Mycopathologia. 1978 Dec 18;65(1-3):13-28. doi: 10.1007/BF00447170.
PMID:106281
Abstract
摘要
相似文献
1
Metabolism of a prototype mycotoxin, aflatoxin B1, and its genetic regulation.一种原型霉菌毒素——黄曲霉毒素B1的代谢及其基因调控。
Mycopathologia. 1978 Dec 18;65(1-3):13-28. doi: 10.1007/BF00447170.
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2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.2,3-二氢-2-（鸟嘌呤-7-基）-3-羟基黄曲霉毒素B1，是在肝微粒体介导的反应以及大鼠肝脏体内形成的黄曲霉毒素B1-DNA或-核糖体RNA加合物的主要酸水解产物。
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Epoxidation of aflatoxin B1 by Aspergillus flavus microsomes in vitro: interaction with DNA and formation of aflatoxin B1-glutathione conjugate.黄曲霉微粒体体外对黄曲霉毒素B1的环氧化作用：与DNA的相互作用及黄曲霉毒素B1-谷胱甘肽共轭物的形成
Chem Biol Interact. 1991;78(1):13-22. doi: 10.1016/0009-2797(91)90099-s.
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Influence of environmental factors on mycotoxin toxicity as evidenced by studies with aflatoxin.黄曲霉毒素研究表明环境因素对霉菌毒素毒性的影响。
Clin Toxicol. 1972;5(4):517-28. doi: 10.3109/15563657208991029.
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Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver.黄曲霉毒素B1在大鼠肝脏重组细胞色素P-450系统中的代谢与激活
Cancer Res. 1982 Mar;42(3):1120-4.
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Genetic analysis of a mutant of Aspergillus flavus producing more aflatoxin B2 than B1.一株产黄曲霉毒素B2多于B1的黄曲霉突变体的遗传分析。
Mycologia. 1977 May-Jun;69(3):556-62.
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Metabolism as a factor in determining the toxic action of the aflatoxins in different animal species.
Food Cosmet Toxicol. 1973 Apr;11(2):287-94. doi: 10.1016/s0015-6264(73)80496-1.
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7,8-Benzoflavone stimulates the metabolic activation of aflatoxin B1 to mutagens by human liver.7,8-苯并黄酮可刺激人肝脏将黄曲霉毒素B1代谢活化为诱变剂。
Biochem Biophys Res Commun. 1978 May 15;82(1):348-55. doi: 10.1016/0006-291x(78)90616-2.
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Effect of sex difference on the in vitro and in vivo metabolism of aflatoxin B1 by the rat.性别差异对大鼠体内外黄曲霉毒素B1代谢的影响。
Cancer Res. 1976 Dec;36(12):4663-71.
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Comparative mutagenicity of palmotoxin Bo and aflatoxins B1 and M1.棕榈毒素Bo与黄曲霉毒素B1和M1的比较致突变性。
J Environ Pathol Toxicol. 1979 Mar-Apr;2(4):1099-107.
引用本文的文献
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Biogenesis of the C20 polyketide, aflatoxin. A review.C20聚酮化合物黄曲霉毒素的生物合成。综述。
Mycopathologia. 1981 Nov 11;76(2):103-14. doi: 10.1007/BF00443757.
本文引用的文献
1
Interactions of aflatoxin with histones and DNA.黄曲霉毒素与组蛋白和DNA的相互作用。
Plant Physiol. 1967 May;42(5):731-5. doi: 10.1104/pp.42.5.731.
2
The action of aflatoxin B1 on the rat liver.黄曲霉毒素B1对大鼠肝脏的作用。
Biochem J. 1967 Jan;102(1):65-75. doi: 10.1042/bj1020065.
3
Aflatoxin B1: binding to DNA in vitro and alteration of RNA metabolism in vivo.黄曲霉毒素B1：体外与DNA结合及体内RNA代谢的改变。
Science. 1966 Mar 25;151(3717):1539-41. doi: 10.1126/science.151.3717.1539.
4
Effect of aflatoxin on transcription in liver cell.黄曲霉毒素对肝细胞转录的影响。
Nature. 1968 Apr 6;218(5136):93-5. doi: 10.1038/218093a0.
5
Differences in the kinetics of benzpyrene hydroxylation by hepatic drug-metabolizing enzymes from phenobarbital and 3-methylcholanthrene-treated rats.苯巴比妥和3-甲基胆蒽处理的大鼠肝脏药物代谢酶对苯并芘羟基化动力学的差异。
Biochem Biophys Res Commun. 1968 Mar 12;30(5):588-93. doi: 10.1016/0006-291x(68)90094-6.
6
Effect of phenobarbital pretreatment on the ability of aflatoxin B 1 to inhibit ribonucleic acid synthesis in rat liver.苯巴比妥预处理对黄曲霉毒素B1抑制大鼠肝脏核糖核酸合成能力的影响。
Biochem Pharmacol. 1970 Nov;19(11):2861-6. doi: 10.1016/0006-2952(70)90025-0.
7
Aflatoxin inhibition of template activity of rat liver chromatin.黄曲霉毒素对大鼠肝脏染色质模板活性的抑制作用。
Biochim Biophys Acta. 1970 Dec 14;224(2):597-607. doi: 10.1016/0005-2787(70)90591-5.
8
The formation of aflatoxins B2a and G2a and their degradation products during the in vitro detoxification of aflatoxin by livers of certain avian and mammalian species.
Food Cosmet Toxicol. 1970 Oct;8(5):527-38. doi: 10.1016/s0015-6264(70)80041-4.
9
Aflatoxin carcinogenesis: inhibition of liver cancer induction in hypophysectomized rats.黄曲霉毒素致癌作用：对垂体切除大鼠肝癌诱发的抑制作用
Int J Cancer. 1969 Jul 15;4(4):422-9. doi: 10.1002/ijc.2910040407.
10
The mechanism of reactions involving Schiff base intermediates. Thiazolidine formation from L-cysteine and formaldehyde.涉及席夫碱中间体的反应机制。L-半胱氨酸与甲醛形成噻唑烷。
J Am Chem Soc. 1971 Nov;93(23):6236-48. doi: 10.1021/ja00752a040.
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