Solomons N W
Center for Studies of Sensory Impairment, Aging, and Metabolism, Guatemala City, Guatemala.
Nutr Rev. 1999 Nov;57(11):350-3. doi: 10.1111/j.1753-4887.1999.tb06912.x.
In a randomized controlled 12-week feeding trial among malnourished, anemic, and largely vitamin A-deficient Ghanaian preschool children, the hypothesis that the ability of provitamin A carotenoids in dark green, leafy vegetables (DGLV) to raise vitamin A status in different formats--with or without fat and with fat plus anthelmintic treatment for intestinal worms--was tested by comparison with a low vitamin A fare and with pure chemical beta-carotene. The 12-week increments in retinol concentrations over baseline ranged from 5% to 44%, but over half of the DGLV-fed population had persistently low circulating retinol. The very modest impact on vitamin A status of these maneuvers to optimize dietary use of provitamin A in DGLV has major implications for public policy to eradicate hypovitaminosis A.
在一项针对营养不良、贫血且大多缺乏维生素A的加纳学龄前儿童进行的为期12周的随机对照喂养试验中，研究了深绿色叶菜类蔬菜（DGLV）中的维生素A原类胡萝卜素以不同形式（有或无脂肪，以及脂肪加肠道蠕虫驱虫治疗）提高维生素A水平的能力，将其与低维生素A食物和纯化学β-胡萝卜素进行比较以进行测试。与基线相比，视黄醇浓度在12周内的增幅为5%至44%，但超过一半食用DGLV的人群循环视黄醇水平持续较低。这些优化DGLV中维生素A原膳食利用的措施对维生素A状态的影响非常有限，这对根除维生素A缺乏症的公共政策具有重大意义。
