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口服金钟柏草、洋靛蓝根、紫锥菊根和淡紫锥菊根混合物的水醇提取物对小鼠抗绵羊红细胞抗体反应的影响。

Effects of an orally applied aqueous-ethanolic extract of a mixture of Thujae occidentalis herba, Baptisiae tinctoriae radix, Echinaceae purpureae radix and Echinaceae pallidae radix on antibody response against sheep red blood cells in mice.

作者信息

Bodinet C, Freudenstein J

机构信息

Schaper & Brümmer GmbH & Co. KG, Research and Development Department, Salzgitter, Germany.

出版信息

Planta Med. 1999 Dec;65(8):695-9. doi: 10.1055/s-1999-14044.

DOI:10.1055/s-1999-14044
PMID:10630107
Abstract

The influence of the oral administration of an aqueous-ethanolic extract of a mixture of Thujae occidentalis herba, Baptisiae tinctoriae radix, Echinaceae purpureae radix and Echinaceae pallidae radix, on the immune response in mice was investigated. The data show that the extract significantly enhances the antibody response to sheep red blood cells (SRBC), induces an increase in the numbers of splenic plaque forming cells (PFC) and an increase in the titer of specific antibodies in the sera of treated animals. The long-term application of the extract over several months also stimulated the PFC-response without affecting spleen weight, total cell yield per spleen or white blood cell count in mice.

摘要

研究了口服由北美香柏叶、洋靛蓝根、紫锥菊根和淡紫松果菊根混合而成的水乙醇提取物对小鼠免疫反应的影响。数据表明,该提取物能显著增强对绵羊红细胞(SRBC)的抗体反应,使脾脏空斑形成细胞(PFC)数量增加,并使受试动物血清中特异性抗体滴度升高。连续数月长期应用该提取物还能刺激PFC反应,且不影响小鼠的脾脏重量、每个脾脏的总细胞产量或白细胞计数。

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