水蛭（蛭纲）中的透明质酸酶活性。

Hyaluronidase activity in leeches (Hirudinea).

作者信息

Hovingh P, Linker A

机构信息

Veterans Administration Hospital, Salt Lake City, UT 84148, USA.

出版信息

Comp Biochem Physiol B Biochem Mol Biol. 1999 Nov;124(3):319-26. doi: 10.1016/s0305-0491(99)00128-5.

DOI:10.1016/s0305-0491(99)00128-5

PMID:10631807

Abstract

The leech hyaluronoglucuronidase (hyaluronidase I) was identified in Erpobdellidae (Nephelopsis obscura and Erpobdella punctata) and Glossiphoniidae (Desserobdella picta) and historically described from Hirudinidae (Hirudo medicinalis). A second leech hyaluronidase (hyaluronidase II) which hydrolyzed only a few bonds to for hyaluronan oligosaccharides larger than 6500 Da, was found in Glossiphoniidae (Helobdella stagnalis, Glossiphonia complanata, Placobdella ornata, and Theromyzon sp.) and in Haemopidae (Haemopis marmorata). The distribution of the two hyaluronidases in leech occurred in both orders (Arhynchobdellida and Rhynchobdellida) and in macrophagous and haematophagous feeding types whereas the liquidosomatophagous leeches only had hyaluronidase II.

摘要

水蛭透明质酸葡萄糖醛酸酶（透明质酸酶I）在蛭科（暗蛭和斑点蛭）和舌蛭科（彩蛭）中被鉴定出来，历史上也曾在医蛭科（医蛭）中被描述过。在舌蛭科（静水扁蛭、扁舌蛭、饰纹扁蛭和兽蛭属）和石蛭科（斑纹石蛭）中发现了第二种水蛭透明质酸酶（透明质酸酶II），它仅水解少数几个键以形成分子量大于6500 Da的透明质酸寡糖。这两种透明质酸酶在水蛭中的分布存在于两个目（无吻蛭目和吻蛭目）以及肉食性和吸血性取食类型中，而吸食体液的水蛭仅含有透明质酸酶II。