Garzon M C, Enjolras O, Frieden I J
Departments of Dermatology and Pediatrics, Columbia University, New York, NY 10032, USA.
J Am Acad Dermatol. 2000 Feb;42(2 Pt 1):275-9. doi: 10.1016/S0190-9622(00)90138-5.
The International Society for the Study of Vascular Anomalies classification is an updated biologic classification that distinguishes vascular tumors from vascular malformations on the basis of clinical and histologic characteristics and biologic behavior.
We propose that in a minority of cases there is an association between vascular tumors and vascular malformations.
We retrospectively identified clinical cases in our medical centers and others reported in the medical literature that demonstrate an association between vascular tumors and vascular malformation clinically or histologically.
We identified several clinical or histologic settings in which vascular tumors and vascular malformations were associated: (1) coexistence of hemangioma and vascular malformation at the same anatomic site or in close proximity; (2) pyogenic granuloma arising within a vascular malformation; (3) hemangioma associated with developmental vascular anomalies; (4) spindle-cell hemangioendothelioma and venous malformation; (5) kaposiform hemangioendothelioma and lymphatic malformation.
The biologic classification of vascular birthmarks distinguishing vascular tumors from vascular malformations is clinically useful and forms the framework for our understanding of vascular anomalies. These examples suggest that in a small minority of patients there is an association between vascular tumors and vascular malformations.
国际血管异常研究学会分类法是一种更新的生物学分类法，它根据临床、组织学特征及生物学行为将血管肿瘤与血管畸形区分开来。
我们提出在少数病例中血管肿瘤与血管畸形之间存在关联。
我们回顾性地在我们的医疗中心及医学文献中报道的其他病例中识别出临床病例，这些病例在临床或组织学上显示血管肿瘤与血管畸形之间存在关联。
我们识别出几种血管肿瘤与血管畸形相关的临床或组织学情况：（1）血管瘤与血管畸形在同一解剖部位或紧邻部位共存；（2）血管畸形内出现化脓性肉芽肿；（3）与发育性血管异常相关的血管瘤；（4）梭形细胞血管内皮瘤与静脉畸形；（5）卡波西样血管内皮瘤与淋巴管畸形。
将血管胎记分为血管肿瘤和血管畸形的生物学分类法在临床上是有用的，并构成了我们理解血管异常的框架。这些例子表明在极少数患者中血管肿瘤与血管畸形之间存在关联。
