Chang Mary Wu
Department of Dermatology, New York University School of Medicine, New York, New York 10016, USA.
Lymphat Res Biol. 2003;1(4):259-65. doi: 10.1089/153968503322758067.
Vascular anomalies comprise a widely heterogenous group of tumors and malformations. Great confusion has arisen because of the term hemangioma has been and is continued to be used to represent a multitude of vascular entities. This review presents the updated classification of vascular anomalies with the goal of clarifying the term hemangioma. In addition, newer clinical concepts in hemangiomas and other vascular tumors is presented. Hemangioma subtypes and hemangioma variants are also discussed, and a brief review of pyogenic granuloma and Kaposiform hemangioendothelioma is provided. Finally, the immunohistochemical marker GLUT1 is reviewed, a marker that heralds a new era in vascular anomalies research.
血管异常包括一大类广泛的异质性肿瘤和畸形。由于“血管瘤”这个术语过去和现在一直被用来代表多种血管病变,因此产生了很大的混淆。本综述介绍了血管异常的最新分类,目的是澄清“血管瘤”这一术语。此外,还介绍了血管瘤和其他血管肿瘤的一些新的临床概念。还讨论了血管瘤亚型和血管瘤变异型,并对化脓性肉芽肿和卡波西样血管内皮瘤进行了简要综述。最后,对免疫组化标志物葡萄糖转运蛋白1(GLUT1)进行了综述,该标志物预示着血管异常研究的新时代。