Enantioselective Addition of Allylic Trimethoxysilanes to Aldehydes Catalyzed by p-Tol-BINAP small middle dotAgF.
作者信息
Yanagisawa A, Kageyama H, Nakatsuka Y, Asakawa K, Matsumoto Y, Yamamoto H
机构信息
Graduate School of Engineering, Nagoya University, CREST, Japan Science and Technology Corporation (JST), Chikusa, Nagoya 464-8603 (Japan).
出版信息
Angew Chem Int Ed Engl. 1999 Dec 16;38(24):3701-3703. doi: 10.1002/(sici)1521-3773(19991216)38:24<3701::aid-anie3701>3.0.co;2-d.
Abstract
Catalytic asymmetric allylation of aldehydes with allylic trimethoxysilanes was achieved with the p-Tol-BINAP small middle dotAgF complex as catalyst [Eq. (a); p-Tol-BINAP=2,2'-bis(di-p-tolylphosphanyl)-1,1'-binaphthyl)]. High anti and enantioselectivities were obtained in the reaction with crotyltrimethoxysilane, irrespective of the configuration at the double bond.
摘要
Zotero 插件