Enomoto T, Sakoda T, Dake Y, Shibano A, Saitoh Y, Takahashi M, Sogo H, Fujiki Y
Department of Otolaryngology, Japanese Red Cross Society Wakayama Medical Center.
Nihon Jibiinkoka Gakkai Kaiho. 1999 Dec;102(12):1311-7. doi: 10.3950/jibiinkoka.102.1311.
The incidence of Japanese cedar pollinosis has been increasing each year in Japan. Japanese cedar pollinosis is a state of allergic response, mediated by IgE. So, it is important to know the state of sensitization against Japanese cedar pollen. The subjects were 1321 nonselective cases who were more than 16 years of age and who live in Wakayama Prefecture. Specific IgE antibodies to Japanese cedar pollen were measured by Lumiward immunoassay system. The results showed that positivity for sera class 2 or higher was 30.9%. Furthermore, the positivity in 1995 was higher than the positivity in either 1985 (13.9%) or 1990 (18.3%). The incidence of specific IgE antibody positivity was higher in males. Also the age distribution of the positivity was highest in the 20-29 years old group, and the positivity was decreased with age. We examined the kinds of factors influencing the positivity of specific IgE antibodies. However, the relation between the positivity of specific IgE antibodies and the various environmental factors was unclear.
在日本，日本雪松花粉症的发病率逐年上升。日本雪松花粉症是一种由IgE介导的过敏反应状态。因此，了解对日本雪松花粉的致敏状态很重要。研究对象为1321例居住在和歌山县、年龄超过16岁的非选择性病例。采用Lumiward免疫分析系统检测针对日本雪松花粉的特异性IgE抗体。结果显示，血清2级及以上阳性率为30.9%。此外，1995年的阳性率高于1985年（13.9%）或1990年（18.3%）。特异性IgE抗体阳性率在男性中较高。而且，阳性率的年龄分布在20 - 29岁组最高，且随年龄增长而降低。我们研究了影响特异性IgE抗体阳性的各种因素。然而，特异性IgE抗体阳性与各种环境因素之间的关系尚不清楚。
