组蛋白在复制染色体上的沉积：在复制叉附近未发现新合成的组蛋白。
Deposition of histone onto the replicating chromosome: newly synthesized histone is not found near the replication fork.
作者信息
Jackson V, Granner D, Chalkley R
出版信息
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2266-9. doi: 10.1073/pnas.73.7.2266.
Abstract
We have studied the site of deposition of newly synthesized histone. It appears to be randomly distributed over the chromosomal material and does not become associated specifically with immediately post-replicational DNA, nor is it deposited in discrete continuous regions distal to the sites of DNA synthesis. The newly synthesized DNA, however, rapidly acquires a complement of chromosomal proteins; presumably, preexisting histones must migrate to become associated with post-replicational DNA.
摘要
我们已经研究了新合成组蛋白的沉积位点。它似乎随机分布在染色体物质上，并不与复制后立即形成的DNA特异性结合，也不是沉积在DNA合成位点远端的离散连续区域。然而，新合成的DNA会迅速获得一组染色体蛋白；据推测，预先存在的组蛋白必须迁移才能与复制后的DNA结合。
相似文献
1
Deposition of histone onto the replicating chromosome: newly synthesized histone is not found near the replication fork.组蛋白在复制染色体上的沉积：在复制叉附近未发现新合成的组蛋白。
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2266-9. doi: 10.1073/pnas.73.7.2266.
2
Deposition of histones onto replicating chromosomes.组蛋白在复制染色体上的沉积。
Proc Natl Acad Sci U S A. 1975 Nov;72(11):4440-4. doi: 10.1073/pnas.72.11.4440.
3
A new method for the isolation of replicative chromatin: selective deposition of histone on both new and old DNA.一种分离复制性染色质的新方法：组蛋白在新旧DNA上的选择性沉积。
Cell. 1981 Jan;23(1):121-34. doi: 10.1016/0092-8674(81)90277-4.
4
Association of newly synthesized histones with replicating and nonreplicating regions of chromatin.新合成组蛋白与染色质复制和非复制区域的关联。
J Biol Chem. 1982 Jul 25;257(14):8507-15.
5
The sites of deposition of newly synthesized histone.新合成组蛋白的沉积位点。
Nucleic Acids Res. 1981 Sep 25;9(18):4563-81. doi: 10.1093/nar/9.18.4563.
6
A reevaluation of new histone deposition on replicating chromatin.对复制染色质上新组蛋白沉积的重新评估。
J Biol Chem. 1981 May 25;256(10):5095-103.
7
Eukaryotic replisome components cooperate to process histones during chromosome replication.真核复制体组件在染色体复制过程中协同作用处理组蛋白。
Cell Rep. 2013 Mar 28;3(3):892-904. doi: 10.1016/j.celrep.2013.02.028. Epub 2013 Mar 14.
8
Replicating chromatin: a tale of histones.复制中的染色质：组蛋白的故事
Biochem Cell Biol. 2009 Feb;87(1):51-63. doi: 10.1139/O08-102.
9
Histone segregation on replicating chromatin.复制染色质上的组蛋白分离
Biochemistry. 1985 Nov 19;24(24):6930-8. doi: 10.1021/bi00345a027.
10
Histone H1 deposition and histone-DNA interactions in replicating chromatin.复制染色质中的组蛋白H1沉积与组蛋白-DNA相互作用。
Proc Natl Acad Sci U S A. 1993 May 1;90(9):3918-22. doi: 10.1073/pnas.90.9.3918.
引用本文的文献
1
Replication-Coupled Chromatin Remodeling: An Overview of Disassembly and Assembly of Chromatin during Replication.复制偶联染色质重塑：复制过程中染色质解聚与组装概述。
Int J Mol Sci. 2021 Jan 23;22(3):1113. doi: 10.3390/ijms22031113.
2
HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding.HAT1 通过结合 H4 启动子来协调组蛋白的产生和乙酰化。
Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034. Epub 2019 Jul 2.
3
PP32 and SET/TAF-Iβ proteins regulate the acetylation of newly synthesized histone H4.PP32和SET/TAF-Iβ蛋白调节新合成组蛋白H4的乙酰化。
Nucleic Acids Res. 2017 Nov 16;45(20):11700-11710. doi: 10.1093/nar/gkx775.
4
Motifs in the amino-terminus of CENP-A are required for its accumulation within the nucleus and at the centromere.CENP-A氨基末端的基序是其在细胞核内和着丝粒处积累所必需的。
Oncotarget. 2017 Jun 20;8(25):40654-40667. doi: 10.18632/oncotarget.17204.
5
DNA polymerase epsilon, acetylases and remodellers cooperate to form a specialized chromatin structure at a tRNA insulator.DNA聚合酶ε、乙酰化酶和重塑因子协同作用，在tRNA绝缘子处形成一种特殊的染色质结构。
EMBO J. 2009 Sep 2;28(17):2583-600. doi: 10.1038/emboj.2009.198. Epub 2009 Jul 23.
6
The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.MYST组蛋白乙酰转移酶对于拟南芥配子体的发育至关重要。
BMC Plant Biol. 2008 Nov 28;8:121. doi: 10.1186/1471-2229-8-121.
7
Monomethylation of lysine 20 on histone H4 facilitates chromatin maturation.组蛋白H4赖氨酸20位点的单甲基化促进染色质成熟。
Mol Cell Biol. 2009 Jan;29(1):57-67. doi: 10.1128/MCB.00989-08. Epub 2008 Nov 10.
8
Stimulation of DNA replication from the polyomavirus origin by PCAF and GCN5 acetyltransferases: acetylation of large T antigen.PCAF和GCN5乙酰转移酶对多瘤病毒起源的DNA复制的刺激作用：大T抗原的乙酰化
Mol Cell Biol. 2002 Nov;22(22):7907-18. doi: 10.1128/MCB.22.22.7907-7918.2002.
9
The sites of deposition of newly synthesized histone.新合成组蛋白的沉积位点。
Nucleic Acids Res. 1981 Sep 25;9(18):4563-81. doi: 10.1093/nar/9.18.4563.
10
Distribution of the core histones H2A.H2B.H3 and H4 during cell replication.核心组蛋白H2A、H2B、H3和H4在细胞复制过程中的分布。
Nucleic Acids Res. 1982 Jan 22;10(2):735-48. doi: 10.1093/nar/10.2.735.
本文引用的文献
1
The cytoplasmic synthesis of histones in hela cells and its temporal relationship to DNA replication.海拉细胞中组蛋白的细胞质合成及其与DNA复制的时间关系。
Proc Natl Acad Sci U S A. 1967 Feb;57(2):409-16. doi: 10.1073/pnas.57.2.409.
2
The biosynthesis of protamine in trout testis. I. Intracellular site of synthesis.鲑鱼睾丸中鱼精蛋白的生物合成。I. 合成的细胞内位点。
Can J Biochem. 1969 Jan;47(1):51-60. doi: 10.1139/o69-009.
3
Initiation of deoxyribonucleic acid replication at the nuclear membrane in human cells.人类细胞核膜处脱氧核糖核酸复制的起始
J Mol Biol. 1968 Apr 14;33(1):225-9. doi: 10.1016/0022-2836(68)90290-8.
4
Histone synthesis in vitro on HeLa cell microsomes. The nature of the coupling to deoxyribonucleic acid synthesis.在海拉细胞微粒体上进行组蛋白的体外合成。与脱氧核糖核酸合成偶联的性质。
J Biol Chem. 1969 Nov 10;244(21):5947-52.
5
Rapidly labeled, polyribosome-associated RNA having the properties of histone messenger.具有组蛋白信使特性的快速标记的多核糖体相关RNA。
Proc Natl Acad Sci U S A. 1967 Nov;58(5):1977-83. doi: 10.1073/pnas.58.5.1977.
6
Interphase chromosomal deoxyribonucleoprotein isolated as a discrete structure from cultured cells.从培养细胞中分离出的作为离散结构的间期染色体脱氧核糖核蛋白。
J Mol Biol. 1974 Jul 5;86(3):649-63. doi: 10.1016/0022-2836(74)90187-9.
7
The structure and function of chromatin.染色质的结构与功能。
Adv Hum Genet. 1972;3:237-431. doi: 10.1007/978-1-4757-4429-3_5.
8
DNA replication sites within nuclei of mammalian cells.哺乳动物细胞核内的DNA复制位点。
Nature. 1973 Jan 5;241(5384):32-6. doi: 10.1038/241032a0.
9
Sites of replication of chromosomal DNA in a eukaryotic cell.真核细胞中染色体DNA的复制位点。
Proc Natl Acad Sci U S A. 1972 Aug;69(8):2300-5. doi: 10.1073/pnas.69.8.2300.
10
On the translational control of histone synthesis. Quantitation of biologically active histone mRNA from synchronized HeLa cells and its translation in different cell-free systems.关于组蛋白合成的翻译控制。来自同步化海拉细胞的生物活性组蛋白mRNA的定量及其在不同无细胞系统中的翻译
Eur J Biochem. 1974 Jun 1;45(1):91-7. doi: 10.1111/j.1432-1033.1974.tb03533.x.
Zotero 插件