Polanczyk C A, Rohde L E, Dec G W, DiSalvo T
Heart Failure and Cardiac Transplantation Unit, Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.
Arch Intern Med. 2000 Feb 14;160(3):325-32. doi: 10.1001/archinte.160.3.325.
Scarce data are available on long-term trends in hospital mortality, length of stay (LOS), and costs in congestive heart failure (CHF).
To assess 10-year trends in the outcomes of patients hospitalized with CHF.
We studied all 6676 patients with a primary discharge diagnosis of CHF hospitalized from January 1, 1986, through July 31, 1996, at an academic tertiary care center. Hospital mortality, LOS, and costs were adjusted for sociodemographic characteristics, comorbidities, invasive procedures, hospital disposition, and LOS where appropriate.
The mean (+/- SD) age of patients was 70+/-13 years; 54.1% were male; 87.0% were white. There was a significant increasing trend in heart failure severity as assessed by a CHF-specific risk-adjustment index. The proportion of patients who underwent invasive procedures (e.g., cardiac catheterization, coronary angioplasty, coronary artery bypass surgery, defibrillator and pacemaker implantation) was significantly higher in the 1994-1996 period. The standardized mortality ratio (observed mortality/predicted mortality) progressively fell during the study period. Compared with patients admitted before 1991, those admitted after 1991 had a 24% lower observed than predicted mortality. Adjusted LOS exhibited a downward trend, ie, 7.7 days in 1986-1987 to 5.6 days in 1994-1996 (P<.001). Unadjusted cost peaked during 1992-1993 and declined thereafter. Adjusted costs in 1994-1996 were not significantly different from those in 1990-1991.
After risk adjustment for sociodemographic characteristics, comorbidities, and disease severity, a significant decrease in in-hospital mortality was observed during the study decade. This decline in hospital mortality occurred in parallel with decreasing LOS and increasing use of cardiac procedures and costs.
关于充血性心力衰竭(CHF)患者的医院死亡率、住院时间(LOS)及费用的长期趋势,现有数据稀缺。
评估CHF住院患者结局的10年趋势。
我们研究了1986年1月1日至1996年7月31日期间在一家学术性三级医疗中心因CHF首次出院诊断而住院的所有6676例患者。根据社会人口统计学特征、合并症、侵入性操作、医院处置情况及适当的住院时间,对医院死亡率、住院时间及费用进行了调整。
患者的平均(±标准差)年龄为70±13岁;54.1%为男性;87.0%为白人。根据CHF特异性风险调整指数评估,心力衰竭严重程度呈显著上升趋势。在1994 - 1996年期间,接受侵入性操作(如心导管检查、冠状动脉成形术、冠状动脉搭桥手术、除颤器和起搏器植入)的患者比例显著更高。在研究期间,标准化死亡率(观察到的死亡率/预测死亡率)逐渐下降。与1991年前入院的患者相比,1991年后入院的患者观察到的死亡率比预测死亡率低24%。调整后的住院时间呈下降趋势,即从1986 - 1987年的7.7天降至1994 - 1996年的5.6天(P <.001)。未调整的费用在1992 - 1993年达到峰值,此后下降。1994 - 1996年的调整后费用与1990 - 1991年无显著差异。
在对社会人口统计学特征、合并症和疾病严重程度进行风险调整后,研究十年期间观察到住院死亡率显著下降。住院死亡率的这种下降与住院时间缩短、心脏手术使用增加及费用增加同时发生。