Pump H, Möhlenkamp S, Sehnert C A, Schimpf S S, Schmidt A, Erbel R, Grönemeyer D H, Seibel R M
Institute of Diagnostic and Interventional Radiology, University of Witten/Herdecke, Schulstr 10, 45468 Muelheim a. d. Ruhr, Germany.
Radiology. 2000 Feb;214(2):447-52. doi: 10.1148/radiology.214.2.r00fe44447.
To evaluate electron-beam computed tomography (CT) for stent localization and noninvasive assessment of stent patency in patients with coronary arterial stents and coronary bypass stents.
CT in the single-section volume mode was performed in 202 patients with 321 coronary arterial stents in 221 vessels to localize the stents. Patency was evaluated in the multisection flow mode with an intravenous bolus injection of contrast material. All electron-beam CT images were reviewed by an observer who had no knowledge of the coronary angiographic results. Electron-beam CT findings were then compared with coronary angiographic findings.
The stents could be visualized and related to the coronary arterial segments in 216 of 221 vessels with electron-beam CT. Of the 221 vessels, 207 were correctly evaluated with electron-beam CT. Compared with coronary angiography, electron-beam CT permitted the detection of 18 of 23 high-grade stenoses (sensitivity, 78%) and correctly depicted the absence of high-grade stenoses in 189 of 193 vessels with stents (specificity, 98%). Altogether, 18 stenoses were detected correctly at electron-beam CT; the interpretation was false-positive in four vessels (positive predictive value, 82% [18/22 vessels]) and false-negative in five (negative predictive value, 97% [189/194 vessels]).
Electron-beam CT may be helpful in localizing intracoronary stents and assessing stent patency noninvasively to delay the intervals between catheterizations in an increasing number of patients.
评估电子束计算机断层扫描(CT)用于冠状动脉支架和冠状动脉搭桥支架患者的支架定位及支架通畅性的无创评估。
对202例患者的221支血管中的321个冠状动脉支架进行单层面容积模式CT扫描以定位支架。采用静脉团注对比剂,在多层面血流模式下评估通畅性。所有电子束CT图像由一名不了解冠状动脉造影结果的观察者进行分析。然后将电子束CT结果与冠状动脉造影结果进行比较。
电子束CT能够在221支血管中的216支血管中显示支架并确定其与冠状动脉节段的关系。在这221支血管中,电子束CT对207支血管评估正确。与冠状动脉造影相比,电子束CT能够检测出23处高度狭窄中的18处(敏感性为78%),并正确显示193支有支架血管中的189支不存在高度狭窄(特异性为98%)。电子束CT共正确检测出18处狭窄;4支血管的判断为假阳性(阳性预测值为82%[18/22支血管]),5支血管为假阴性(阴性预测值为97%[189/194支血管])。
电子束CT有助于冠状动脉内支架的定位,并无创评估支架通畅性,从而延长越来越多患者的导管插入术间隔时间。