Boronin A M, Anisimova L A, Bogdanova V V
Antibiotiki. 1979 Jan;24(1):37-41.
The study of 40 clinical strains of Ps. aeruginosa isolated from the wound surfaces of the patients showed that all the isolates were resistant to one or several antibiotics. The number of the strains resistant to 5, 4, 3, 2 or 1 drug was 5, 22.5, 25. 30 or 17.5 per cent respectively. Fifteen strains carried resistance plasmids capable of conjugative transfer. Eleven out of 21 plasmids controlled resistance to chloramphenicol, 7 plasmids controlled resistance to streptomycin and sulfanylamides, 1 plasmid controlled resistance to streptomycin and chloramphenicol. The presence of two types of the plasmids controlling resistance to chloramphenicol and streptomycin + sulfanylamides respectively was found. All the plasmids proved to be capable of conjugative transfer between the strains of Ps. aeruginosa ML (PAO). The frequency of the plasmid conjugative transfer in such crosses ranged from 10(-6) to 10(-3). Most of the plasmids belonged to the incompatibility groups P-2 and P-7. One plasmid belonged to the incompatibility group P-5. It should be noted that about a half of the plasmids (11 out of 21) belonged to the incompatibility group P-7 which up to the present time was conditional, since was represented by a single plasmid Rms 148.
对从患者伤口表面分离出的40株铜绿假单胞菌临床菌株的研究表明，所有分离株对一种或几种抗生素耐药。对5种、4种、3种、2种或1种药物耐药的菌株数量分别为5%、22.5%、25%、30%或17.5%。15株携带可进行接合转移的耐药质粒。21种质粒中有11种控制对氯霉素的耐药性，7种质粒控制对链霉素和磺胺类药物的耐药性，1种质粒控制对链霉素和氯霉素的耐药性。发现分别存在两种控制对氯霉素和链霉素+磺胺类药物耐药性的质粒类型。所有质粒均证明可在铜绿假单胞菌ML（PAO）菌株之间进行接合转移。此类杂交中质粒接合转移的频率范围为10^(-6)至10^(-3)。大多数质粒属于不相容群P-2和P-7。一种质粒属于不相容群P-5。应当指出，约一半的质粒（21种中的11种）属于不相容群P-7，截至目前该群是条件性的，因为它仅由单个质粒Rms 148代表。
