Leboeuf-Yde C
Nordic Institute for Chiropractic and Clinical Biomechanics, Odense, Denmark.
Spine (Phila Pa 1976). 2000 Jan 15;25(2):226-37. doi: 10.1097/00007632-200001150-00015.
A systematic review of the epidemiologic literature.
To establish if body weight is truly associated with low back pain (LBP) and whether the link may be causal.
Because obesity and LBP are prevalent in western society, it is of interest to establish whether obesity can induce LBP.
Fifty-six original research reports, reporting on 65 studies published between 1965 and 1997, were systematically reviewed for the frequency of positive associations between body weight and LBP. In addition, the presence of positive findings was examined in relation to several study characteristics. Based on these results, only studies emanating from the general population with a sample size exceeding 3000 were included in the additional search for causality using some of the classical Bradford-Hill criteria. The review was carried out by the author, blindly at 2 months' interval.
Thirty-two percent of all the studies report a statistically significant positive weak association between body weight and LBP. Studies that fulfilled the post hoc criteria never report a rate ratio above 2, but there is possibly a positive biological gradient. These studies had no information on temporality or reversibility and there was no obvious consistency of findings.
Due to lack of evidence, body weight should be considered a possible weak risk indicator, but there is insufficient data to assess if it is a true cause of LBP.
对流行病学文献的系统综述。
确定体重是否真的与腰痛(LBP)相关,以及这种关联是否可能具有因果关系。
由于肥胖和腰痛在西方社会普遍存在,因此确定肥胖是否会引发腰痛很有意义。
系统回顾了56篇原始研究报告,这些报告报道了1965年至1997年间发表的65项研究中体重与腰痛之间正相关的频率。此外,还根据若干研究特征检查了阳性结果的存在情况。基于这些结果,在使用一些经典的布拉德福德-希尔标准进行的额外因果关系搜索中,仅纳入了来自一般人群且样本量超过3000的研究。该综述由作者进行,间隔两个月进行一次盲审。
所有研究中有32%报告体重与腰痛之间存在统计学上显著的正弱关联。符合事后标准的研究从未报告过率比高于2,但可能存在正生物学梯度。这些研究没有关于时间顺序或可逆性的信息,且研究结果也没有明显的一致性。
由于缺乏证据,体重应被视为一个可能的弱风险指标,但没有足够的数据来评估它是否是腰痛的真正原因。