Ishii A, Nagai N, Arai M, Kawabata M, Matsuo T, Bobogare A, Leafasia J
Department of Medical Zoology, Jichi Medical School, Tochigi, Japan.
Parassitologia. 1999 Sep;41(1-3):383-4.
Malaria control by chemotherapy has been established in rural villages of Guadalcanal, the Solomon Islands, following field trials. As a selective primary health care activity, mobile unit teams visited villages once or twice a year to detect malaria positives and gave chloroquine and primaquine to treat the infection and interrupt the transmission. On site diagnosis was by the use of acridine orange fluorescent staining or the ICTPf commercial diagnostic kit. To avoid possible haemolytic crises, a new single step screening method of G6PD deficiency was introduced. This approach has been accepted well by villagers and proved to be an efficient and feasible control method even in remote rural villages with endemic malaria transmission. Epidemiological modelling of the situation predicts reduction of prevalence in five years.
在所罗门群岛瓜达尔卡纳尔岛的农村地区,经过现场试验后,已通过化疗实现了疟疾控制。作为一项选择性初级卫生保健活动,流动医疗队每年走访村庄一到两次,以检测疟疾病例,并给予氯喹和伯氨喹来治疗感染并阻断传播。现场诊断采用吖啶橙荧光染色法或ICTPf商业诊断试剂盒。为避免可能出现的溶血性危机,引入了一种新的葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症单步筛查方法。这种方法深受村民欢迎,并且证明即使在疟疾流行传播的偏远农村地区,也是一种高效可行的控制方法。对这种情况的流行病学建模预测,患病率将在五年内下降。