Cox N H, Colver G B, Paterson W D
Department of Dermatology, Cumberland Infirmary, Carlisle, UK.
J R Soc Med. 1998 Dec;91(12):634-7. doi: 10.1177/014107689809101206.
Ascending cellulitis of the leg is a common emergency. An audit was conducted in two district general hospitals to determine how it is managed and the long-term morbidity, and to formulate a treatment strategy. Case notes were reviewed for 92 patients admitted to hospital under adult specialties. Mean duration of inpatient therapy was 10 days. A likely portal of entry was identified in 51/92 cases, of which the commonest were minor injuries and tinea pedis. Pathogens were rarely identified, group G streptococci being the single most frequent organism. Benzylpenicillin was administered in only 43 cases. Long-term morbidity, identified in 8 of 70 patients with over six months' follow-up, included persistent oedema (6) and leg ulceration (2); an additional 19 patients had either suffered previous episodes or experienced a further episode subsequently. Ascending cellulitis of the leg has substantial short-term and long-term morbidity. Important but often neglected therapeutic suggestions are the inclusion of benzylpenicillin in all cases without a contraindication, assessment and treatment of tinea pedis, use of support hosiery, and serological testing for streptococci to confirm the diagnosis in retrospect. The high frequency of recurrent episodes suggests that longer courses of penicillin, or penicillin prophylaxis, might be useful.
腿部上行性蜂窝织炎是一种常见的急症。在两家区综合医院进行了一项审计,以确定其治疗方式及长期发病率,并制定治疗策略。对92例入住成人专科病房的患者病历进行了回顾。住院治疗的平均时长为10天。在92例病例中有51例确定了可能的感染入口,其中最常见的是轻伤和足癣。很少能鉴定出病原体,G组链球菌是最常见的单一病原体。仅43例患者使用了苄星青霉素。在70例接受了超过6个月随访的患者中,有8例出现长期发病情况,包括持续性水肿(6例)和腿部溃疡(2例);另有19例患者既往曾有过发作或随后又经历了一次发作。腿部上行性蜂窝织炎有相当严重的短期和长期发病率。重要但常被忽视的治疗建议包括:在无禁忌证的所有病例中使用苄星青霉素、评估和治疗足癣、使用弹力袜,以及进行链球菌血清学检测以便事后确诊。复发率高表明较长疗程的青霉素治疗或青霉素预防可能有效。