Vaugelade P, Hoebler C, Bernard F, Guillon F, Lahaye M, Duee P H, Darcy-Vrillon B
LNSA, INRA, Jouy-en-Josas, France.
Reprod Nutr Dev. 2000 Jan-Feb;40(1):33-47. doi: 10.1051/rnd:2000118.
We have investigated the possible effects of algal polysaccharides on postprandial blood glucose and insulin responses in an animal model, the pig. Three seaweed fibres of different viscosities, extracted from Palmaria palmata (PP), Eucheuma cottonii (EC), or Laminaria digitata (LD), were compared to purified cellulose (CEL). Blood glucose and plasma insulin levels were monitored and intestinal absorption quantified for 8 h following a high carbohydrate test-meal supplemented with 5% fibre. Digestive contents were also sampled, 5 h postprandial. As compared to CEL, PP had no effect on glucose and insulin responses. The latter decreased with EC, but glucose absorption balance was not modified. LD addition resulted in a dramatically reduced glucose absorption balance, accompanied by a higher amount of starch left in the small intestine. Among polysaccharides tested, only the highly viscous alginates could affect intestinal absorption of glucose and insulin response.
我们在猪这一动物模型中研究了藻类多糖对餐后血糖及胰岛素反应的潜在影响。将从掌状红皮藻（PP）、麒麟菜（EC）或海带（LD）中提取的三种不同粘度的海藻纤维与纯化纤维素（CEL）进行了比较。在补充了5%纤维的高碳水化合物测试餐后，监测血糖和血浆胰岛素水平，并对8小时内的肠道吸收进行定量。餐后5小时也采集了消化内容物样本。与CEL相比，PP对血糖和胰岛素反应没有影响。EC会使后者降低，但葡萄糖吸收平衡未改变。添加LD导致葡萄糖吸收平衡显著降低，同时小肠中残留的淀粉量增加。在所测试的多糖中，只有高粘性的藻酸盐会影响葡萄糖的肠道吸收和胰岛素反应。
