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Detection of Epstein-Barr virus in invasive breast cancers.浸润性乳腺癌中爱泼斯坦-巴尔病毒的检测
J Natl Cancer Inst. 1999 Aug 18;91(16):1376-81. doi: 10.1093/jnci/91.16.1376.
2
Effect of material deprivation on Epstein-Barr virus infection in Hodgkin's disease in the West Midlands.西米德兰兹郡霍奇金淋巴瘤中物质剥夺对爱泼斯坦-巴尔病毒感染的影响
Br J Cancer. 1999 May;80(3-4):604-8. doi: 10.1038/sj.bjc.6690398.
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Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins.爱泼斯坦-巴尔病毒的潜伏膜蛋白1与JAK3相互作用并激活信号转导和转录激活因子蛋白。
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Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production.爱泼斯坦-巴尔病毒编码的潜伏膜蛋白1对p38丝裂原活化蛋白激酶途径的激活共同调节白细胞介素-6和白细胞介素-8的产生。
J Biol Chem. 1999 Jun 4;274(23):16085-96. doi: 10.1074/jbc.274.23.16085.
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Detection of Epstein-Barr virus (EBV) in hepatocellular carcinoma tissue: a novel EBV latency characterized by the absence of EBV-encoded small RNA expression.肝细胞癌组织中爱泼斯坦-巴尔病毒(EBV)的检测:一种以缺乏EBV编码的小RNA表达为特征的新型EBV潜伏状态。
Virology. 1999 Apr 10;256(2):196-202. doi: 10.1006/viro.1999.9619.
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Epstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2.爱泼斯坦-巴尔病毒编码的潜伏膜蛋白1通过一种涉及TRADD和TRAF2的机制,经由其极端的C末端激活JNK途径。
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Analysis of major histocompatibility complex class I, TAP expression, and LMP2 epitope sequence in Epstein-Barr virus-positive Hodgkin's disease.爱泼斯坦-巴尔病毒阳性霍奇金淋巴瘤中主要组织相容性复合体I类、抗原加工相关转运体表达及低分子量蛋白酶体2表位序列分析
Blood. 1998 Oct 1;92(7):2477-83.
8
BCL-6 gene mutations in posttransplantation lymphoproliferative disorders predict response to therapy and clinical outcome.移植后淋巴细胞增生性疾病中的BCL-6基因突变可预测治疗反应和临床结果。
Blood. 1998 Oct 1;92(7):2294-302.
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Epstein-Barr virus and Hodgkin's disease: further evidence for the three disease hypothesis.
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Jaks and STATs: biological implications.激酶和信号转导及转录激活蛋白:生物学意义。
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爱泼斯坦-巴尔病毒及其与人类癌症的关联。

The Epstein-Barr virus and its association with human cancers.

作者信息

Baumforth K R, Young L S, Flavell K J, Constandinou C, Murray P G

机构信息

Biomedical Research Laboratories, School of Health Sciences, University of Wolverhampton, UK.

出版信息

Mol Pathol. 1999 Dec;52(6):307-22. doi: 10.1136/mp.52.6.307.

DOI:10.1136/mp.52.6.307
PMID:10748864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC395716/
Abstract

The Epstein-Barr virus (EBV) has been linked to the development of a variety of human malignancies, including Burkitt's lymphoma, Hodgkin's disease, nasopharyngeal carcinoma, some T cell lymphomas, post-transplant lymphoproliferative disease, and more recently, certain cancers of the stomach and smooth muscle. This review summarizes these associations and in particular the role of the viral latent genes in the transformation process.

摘要

爱泼斯坦-巴尔病毒(EBV)与多种人类恶性肿瘤的发生有关,包括伯基特淋巴瘤、霍奇金病、鼻咽癌、某些T细胞淋巴瘤、移植后淋巴细胞增殖性疾病,以及最近发现的某些胃癌和平滑肌肉癌。本综述总结了这些关联,特别是病毒潜伏基因在转化过程中的作用。