Katz J
Department of International Health, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205-2103, USA.
Invest Ophthalmol Vis Sci. 2000 Apr;41(5):1012-6.
To compare the rates of progression of visual field defects in glaucoma patients, by using the Glaucoma Change Probability program based on pattern deviation and total deviation probability maps.
The incidence of progression of visual field loss among 67 eyes of 56 glaucoma patients with an average of 6 years of follow-up was estimated by applying the criteria set by the Early Manifest Glaucoma Treatment study, which uses the output from the Glaucoma Change Probability (GCP) program of the Humphrey Field Analyzer (San Leandro, CA) based on pattern deviation probability maps. This incidence estimate was compared with one obtained by applying the same criteria but using the GCP program based on total deviation probability maps.
The 6-year incidence of progression among patients with glaucoma was 23.2% and 35.7% using the GCP program based on pattern deviation and total deviation probability maps, respectively. Not all patients in whom visual field loss progressed according to pattern deviation also showed progression according to total deviation.
The GCP program based on pattern deviation probability maps appears to screen out patients in whom progression of visual field defects may be due to diffuse loss from cataract, but the pattern deviation maps may also be identifying other types of field loss not detected by the total deviation maps.
通过使用基于模式偏差和总偏差概率图的青光眼变化概率程序,比较青光眼患者视野缺损的进展率。
应用早期显性青光眼治疗研究设定的标准,估计56例青光眼患者67只眼平均随访6年期间视野丧失进展的发生率,该标准使用基于模式偏差概率图的Humphrey视野分析仪(加利福尼亚州圣莱安德罗)的青光眼变化概率(GCP)程序输出。将该发生率估计值与应用相同标准但使用基于总偏差概率图的GCP程序获得的估计值进行比较。
使用基于模式偏差和总偏差概率图的GCP程序,青光眼患者6年进展发生率分别为23.2%和35.7%。并非所有根据模式偏差视野丧失进展的患者根据总偏差也显示进展。
基于模式偏差概率图的GCP程序似乎筛出了视野缺损进展可能归因于白内障弥漫性丧失的患者,但模式偏差图也可能识别出总偏差图未检测到的其他类型的视野丧失。