Uhara H, Kawachi S, Saida T
Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.
J Dermatol. 2000 Mar;27(3):214-6. doi: 10.1111/j.1346-8138.2000.tb02152.x.
We report a 53-year old man with symmetrical nonpitting edema, conjunctivitis, and acneiform eruptions on the face. Histopathological examination showed perifollicular lymphohistiocytic infiltration and telangiectasias in the upper dermis. Loosely aggregated non-caseating granulomas were scattered through the dermis; some of them were seen in the perifollicular regions. The patient was treated with fleroxacin (100 mg/day, orally) for two weeks with a marked reduction of both solid facial edema and periorbital edema.