Sobel J D
Division of Infectious Diseases, Wayne State University School of Medicine, Detroit Medical Center, Michigan 48201, USA.
Annu Rev Med. 2000;51:349-56. doi: 10.1146/annurev.med.51.1.349.
Bacterial vaginosis represents a unique upheaval of the complex vaginal bacterial flora with disappearance of lactobacilli and overgrowth of Gardnerella vaginalis and resident anaerobic vaginal bacteria. Little progress has occurred in identifying causal factors, although the pathophysiology of this syndrome is better understood. Although symptoms are easily recognizable, obstetric and gynecologic complications continue to increase in number. Bacterial vaginosis is far more than a nuisance infection. Problems with diagnosis continue to dominate clinical practice, although new tests have been introduced. Therapeutic options have increased, although recurrent disease remains common, and management of this common complication constitutes a major challenge.
细菌性阴道病表现为复杂阴道菌群的独特紊乱，乳酸杆菌消失，阴道加德纳菌和阴道常驻厌氧菌过度生长。尽管对该综合征的病理生理学有了更好的理解，但在确定病因方面进展甚微。虽然症状易于识别，但妇产科并发症的数量仍在不断增加。细菌性阴道病远不止是一种令人讨厌的感染。尽管已经引入了新的检测方法，但诊断问题仍然主导着临床实践。治疗选择有所增加，尽管复发性疾病仍然很常见，而对这种常见并发症的管理构成了一项重大挑战。
