Sato S, Kumada S, Koji T, Okaniwa M
Department of Pediatrics, Musashino Red Cross Hospital, Tokyo, Japan.
Pediatr Neurol. 2000 Apr;22(4):318-21. doi: 10.1016/s0887-8994(99)00150-2.
Two patients, a 3-year-old female and a 1-year-old female, both with a focal encephalopathic process associated with influenza A virus infection, are reported. Both children had neuropsychologic signs suggesting frontal and limbic dysfunction, without disturbances of consciousness or motor function, and had good recoveries. The results of single-photon emission computed tomography and electroencephalography support the finding of reversible impairment of the frontal and limbic areas. Focal reversible encephalopathy has rarely been reported in association with influenza virus infection, although it often provokes diffuse encephalopathies, with a poor prognosis.
报告了两名患者，一名3岁女性和一名1岁女性，均患有与甲型流感病毒感染相关的局灶性脑病过程。两名儿童均有提示额叶和边缘系统功能障碍的神经心理学体征，无意识或运动功能障碍，且恢复良好。单光子发射计算机断层扫描和脑电图结果支持额叶和边缘系统区域可逆性损伤的发现。尽管流感病毒感染常引发弥漫性脑病且预后较差，但与流感病毒感染相关的局灶性可逆性脑病鲜有报道。
