Kerr W C, Fillmore K M, Marvy P
University of California-San Francisco, Laurel Heights 94143-0612, USA.
Addiction. 2000 Mar;95(3):339-46. doi: 10.1046/j.1360-0443.2000.9533394.x.
To compare beverage-specific per capita consumption and total alcohol consumption's associations with cirrhosis mortality rates in multiple countries.
Pooled cross-sectional time-series analysis.
Australia, Canada, New Zealand, the United Kingdom and the United States during the years 1953-1993.
National level data on per capita total alcohol, beer, wine and spirits consumption and standardized all-cause cirrhosis mortality rates.
Significant associations with cirrhosis mortality are found for both total ethanol and spirits. Spirits consumption is found to make up the majority of the effect of alcoholic beverage consumption on cirrhosis mortality and the model including only spirits is found to fit the data at least as well as the model including only total ethanol consumption. The lag relationship between all alcohol types and cirrhosis is found to be short with only present and 1 year's lagged consumption having significant associations.
Spirits consumption rather than beer or wine is associated with cirrhosis mortality in this group of primarily beer-drinking countries. This finding offers important clues to understanding the drinking behaviors associated with cirrhosis mortality on the individual level.
比较多个国家中特定饮料的人均消费量以及总酒精消费量与肝硬化死亡率之间的关联。
汇总横断面时间序列分析。
1953年至1993年期间的澳大利亚、加拿大、新西兰、英国和美国。
人均总酒精、啤酒、葡萄酒和烈酒消费量的国家级数据以及标准化的全因肝硬化死亡率。
总乙醇和烈酒与肝硬化死亡率均存在显著关联。研究发现，烈酒消费在酒精饮料消费对肝硬化死亡率的影响中占主要部分，且仅包含烈酒的模型对数据的拟合效果至少与仅包含总乙醇消费量的模型相同。所有酒精类型与肝硬化之间的滞后关系较短，仅当前消费量和滞后1年的消费量存在显著关联。
在这组主要饮用啤酒的国家中，与肝硬化死亡率相关的是烈酒消费而非啤酒或葡萄酒消费。这一发现为从个体层面理解与肝硬化死亡率相关的饮酒行为提供了重要线索。
