Gruenewald P J, Ponicki W R
Prevention Research Center, Berkeley, California 94704, USA.
J Stud Alcohol. 1995 Nov;56(6):635-41. doi: 10.15288/jsa.1995.56.635.
The goal of the current study was to evaluate the extent to which beverage specific alcohol sales (beer, wine and distilled spirits) are associated with cirrhosis mortality rates.
Cirrhosis mortality rates were related to measures of beverage specific alcohol sales data from 50 states in the United States taken over 12 years. Cirrhosis mortality rates were regressed over beverage specific alcohol sales in a time series cross-sectional analysis that included age compositions of state populations, measures of the availability of health care, population density, proscriptions on alcohol use, income, tourism and nighttime traffic fatality crash rates as covariates.
Controlling for empirically observed first order autocorrelated errors in estimation, and the effects of other related covariates, the analyses showed that there was a beverage specific effect of distilled spirits sales on cirrhosis mortality rates. One percent increases in spirits sales were reflected in .282% increases in cirrhosis mortality rates. There were no significant effects for either beer or wine sales.
The relationship of spirits sales to cirrhosis mortality rates may be explained most reasonably by the association of chronic heavy drinking with the consumption of spirits.
本研究的目的是评估特定酒类(啤酒、葡萄酒和蒸馏酒)的酒精销售量与肝硬化死亡率之间的关联程度。
肝硬化死亡率与美国50个州12年期间特定酒类酒精销售数据的测量值相关。在时间序列横断面分析中,将肝硬化死亡率对特定酒类酒精销售量进行回归分析,该分析纳入了州人口的年龄构成、医疗保健可及性的测量值、人口密度、酒精使用禁令、收入、旅游业和夜间交通死亡事故率作为协变量。
在估计中控制经验观察到的一阶自相关误差以及其他相关协变量的影响后,分析表明蒸馏酒销售对肝硬化死亡率有特定酒类的影响。烈酒销售量增加1%,肝硬化死亡率相应增加0.282%。啤酒和葡萄酒销售均无显著影响。
烈酒销售与肝硬化死亡率之间的关系最合理的解释可能是慢性重度饮酒与烈酒消费之间的关联。