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成人桡骨远端骨折的保守治疗干预措施。

Conservative interventions for treating distal radial fractures in adults.

作者信息

Handoll H H, Madhok R

机构信息

East Riding Health Authority, Grange Park Lane, Willerby, East Yorkshire, UK, HU10 6DT.

出版信息

Cochrane Database Syst Rev. 2000(2):CD000314. doi: 10.1002/14651858.CD000314.

Abstract

BACKGROUND

Fracture of the distal radius is a common clinical problem particularly in elderly white women with osteoporosis, in whom the lifetime risk of this injury has been estimated as 15 per cent.

OBJECTIVES

To determine the most appropriate conservative treatment for fractures (such as Colles') of the distal radius in adults.

SEARCH STRATEGY

We searched the Cochrane Musculoskeletal Injuries Group trials register, Medline and reference lists of trials. Date of the most recent search: April 1998.

SELECTION CRITERIA

Randomised or quasi-randomised clinical trials involving skeletally mature patients with a fracture of the distal radius, which compared commonly applied conservative interventions for fracture fixation. These included the application of an external support (plaster cast or brace) and fracture manipulation.

DATA COLLECTION AND ANALYSIS

All trials, judged as fitting the selection criteria by both reviewers, were independently assessed by both reviewers for methodological quality. Data were extracted for anatomical, functional and clinical, including complications, outcomes. The trials were grouped into categories relating to cast position, extent and duration of immobilisation, use of braces, cast material and fracture manipulation. Although quantitative data from some trials are presented, the lack of good quality trials and trial heterogeneity inhibited pooling of results.

MAIN RESULTS

Over 50 randomised trials comparing treatment options for distal radial fractures were identified. Twenty nine trials of these, involving a total of 3199 mainly female and older patients, met the inclusion criteria for this review. Comprehensive details of the individual trials are provided in tabular form, and their results, grouped as indicated above, have been presented in text and analyses tables. The poor quality and heterogeneity in terms of patient characteristics, interventions compared and outcome measurement, of the included trials meant that no meta-analyses were undertaken.

REVIEWER'S CONCLUSIONS: There is insufficient evidence from randomised trials to determine which methods of conservative treatment are the most appropriate for the more common types of distal radial fractures in adults. Therefore, at present, practitioners applying conservative management should use an accepted technique with which they are familiar, and which is cost-effective from the perspective of their provider unit. Whilst tempting, any call for further research to clarify the most appropriate conservative treatment for this common fracture must be resisted for now. Instead it is important to reflect on the issues raised in this review, to ascertain patient preferences, prioritise researchable questions and undertake a systematic programme of research after agreeing a core data set for classification of fractures and outcomes.

摘要

背景

桡骨远端骨折是一个常见的临床问题,尤其在患有骨质疏松症的老年白人女性中,据估计其一生中发生这种损伤的风险为15%。

目的

确定成人桡骨远端骨折(如科雷氏骨折)最合适的保守治疗方法。

检索策略

我们检索了Cochrane肌肉骨骼损伤组试验注册库、Medline以及试验的参考文献列表。最近一次检索日期:1998年4月。

选择标准

随机或半随机临床试验,涉及骨骼成熟的桡骨远端骨折患者,比较了常用的骨折固定保守干预措施。这些措施包括应用外部支撑(石膏或支具)和骨折手法复位。

数据收集与分析

两位评审员均判定符合选择标准的所有试验,由两位评审员独立评估其方法学质量。提取了有关解剖、功能和临床方面的数据,包括并发症、结果。试验被分为与石膏位置、固定范围和持续时间、支具使用、石膏材料以及骨折手法复位相关的类别。尽管呈现了一些试验的定量数据,但由于缺乏高质量试验以及试验的异质性,结果无法合并。

主要结果

共识别出50多项比较桡骨远端骨折治疗方案的随机试验。其中29项试验,共涉及3199名主要为女性和老年患者,符合本综述的纳入标准。各试验的详细信息以表格形式呈现,其结果按上述方式分组后,已在正文和分析表中列出。纳入试验在患者特征、比较的干预措施和结果测量方面质量较差且存在异质性,这意味着未进行荟萃分析。

评审员结论

随机试验中没有足够的证据来确定哪种保守治疗方法最适合成人中较常见类型的桡骨远端骨折。因此,目前采用保守治疗的从业者应使用他们熟悉的、从其医疗单位角度来看具有成本效益的公认技术。虽然很诱人,但目前必须抵制任何要求进一步研究以明确这种常见骨折最合适保守治疗方法的呼吁。相反,重要的是反思本综述中提出的问题,确定患者偏好,对可研究问题进行优先排序,并在商定骨折和结果分类的核心数据集后开展系统的研究计划。

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