Handoll H H, Madhok R
c/o Dr Elizabeth Royle, Cochrane Peripheral Vascular Diseases Group, Public Health Sciences, The University of Edinburgh Medical School, Teviot Place, Edinburgh, UK, EH8 9AG.
Cochrane Database Syst Rev. 2003;2003(1):CD003763. doi: 10.1002/14651858.CD003763.
Fracture of the distal radius is a common clinical problem, particularly in older white women with osteoporosis. Displaced fractures are usually reduced using closed reduction methods, which are non-surgical and generally comprise traction and manipulation, and the resulting position stabilised by external means, typically plaster cast immobilisation.
To examine the evidence for the relative effectiveness of different methods of closed reduction for displaced fractures of the distal radius in adults.
We searched the Cochrane Musculoskeletal Injuries Group specialised register (to July 2002), the Cochrane Controlled Trials Register (The Cochrane Library, Issue 3, 2002), MEDLINE (1966 to July week 4 2002), EMBASE (1988 to 2002 week 31), CINAHL (1982 to June week 4 2002), the UK National Research Register (Issue 2, 2002) and reference lists of articles. We also handsearched the British Volume of the Journal of Bone and Joint Surgery supplements (1996 onwards), and abstracts of the American Orthopaedic Trauma Association annual meetings.
Randomised or quasi-randomised clinical trials evaluating different methods of closed reduction. We also included trials in which the use (or not) of anaesthesia could be classed as a co-intervention.
All trials judged as fitting the selection criteria by both reviewers were independently assessed by both reviewers for methodological quality. Data were extracted independently by one reviewer and checked by the other. Quantitative data are presented using relative risks or mean differences together with 95 per cent confidence limits. No pooling was possible.
Three trials involving a total of 404, mainly female and older, patients with displaced fractures of the distal radius were included. These failed to assess functional outcome, and only one trial reported on complications. One trial found no statistically significant differences between mechanical reduction using finger trap traction and manual reduction in anatomical outcomes. One trial compared a novel method of manual reduction where the non-anaesthetised patient actively provided counter-traction versus traditional manual reduction under intravenous regional anaesthesia. While patients of the novel method group suffered more, yet not intolerable, pain during the reduction procedure, the latter was shorter in duration. No differences in anatomical outcome were detected. The third study compared mechanical reduction involving a special device without anaesthesia versus manual reduction under haematoma block (local anaesthesia). Less pain during the reduction procedure was recorded for the mechanical traction group. Both methods yielded similar radiological results. Fewer patients in the mechanical traction group had signs of neurological impairment, mainly finger numbness, at five weeks but this difference was not statistically significant by one year.
REVIEWER'S CONCLUSIONS: There was insufficient evidence from comparisons tested within randomised trials to establish the relative effectiveness of different methods of closed reduction used in the treatment of displaced fractures of the distal radius in adults. Given the many unresolved questions over the management of these fractures, we suggest an integrated programme of research, which includes consideration of reduction methods, is the way forward.
桡骨远端骨折是一个常见的临床问题,在患有骨质疏松症的老年白人女性中尤为常见。移位骨折通常采用闭合复位方法进行复位,这是非手术方法,一般包括牵引和手法复位,复位后的位置通过外部手段固定,通常是石膏固定。
研究成人桡骨远端移位骨折不同闭合复位方法相对有效性的证据。
我们检索了Cochrane肌肉骨骼损伤组专业注册库(截至2002年7月)、Cochrane对照试验注册库(《Cochrane图书馆》,2002年第3期)、MEDLINE(1966年至2002年7月第4周)、EMBASE(1988年至2002年第31周)、CINAHL(1982年至2002年6月第4周)、英国国家研究注册库(2002年第2期)以及文章的参考文献列表。我们还手工检索了《骨与关节外科杂志》英国卷增刊(1996年起)以及美国矫形外科学会创伤协会年会摘要。
评估不同闭合复位方法的随机或半随机临床试验。我们还纳入了将麻醉的使用(或不使用)可归类为共同干预措施的试验。
两位评审员均判定符合选择标准的所有试验,由两位评审员独立评估其方法学质量。数据由一位评审员独立提取并由另一位评审员检查。定量数据以相对风险或均值差异以及95%置信区间呈现。无法进行合并分析。
纳入了三项试验,共404例主要为女性且年龄较大的桡骨远端移位骨折患者。这些试验未评估功能结局,仅有一项试验报告了并发症情况。一项试验发现,使用指套牵引进行机械复位与手法复位在解剖学结局方面无统计学显著差异。一项试验比较了一种新的手法复位方法,即未麻醉的患者主动提供对抗牵引与静脉区域麻醉下的传统手法复位。虽然新方法组的患者在复位过程中疼痛更剧烈,但尚可忍受,而后者的持续时间更短。未检测到解剖学结局方面的差异。第三项研究比较了使用特殊装置且不进行麻醉的机械复位与血肿内阻滞(局部麻醉)下的手法复位。机械牵引组在复位过程中的疼痛较轻。两种方法产生的放射学结果相似。机械牵引组在五周时出现神经损伤体征(主要为手指麻木) 的患者较少,但到一年时这种差异无统计学意义。
随机试验中所测试的比较缺乏足够证据来确定成人桡骨远端移位骨折不同闭合复位方法的相对有效性。鉴于这些骨折的治疗存在许多未解决的问题,我们建议开展一项综合研究计划,其中包括考虑复位方法,这才是前进的方向。