Strother C M, Unal O, Frayne R, Turk A, Omary R, Korosec F R, Mistretta C A
Department of Radiology, University of Wisconsin Health Sciences Center, 600 Highland Ave, Madison, WI 53792-3252, USA.
Radiology. 2000 May;215(2):516-9. doi: 10.1148/radiology.215.2.r00ma34516.
To evaluate the feasibility of using magnetic resonance (MR) imaging to guide and monitor endovascular therapeutic procedures.
Endovascular therapeutic procedures were performed with MR imaging guidance in eight dogs by using a 1.5-T MR unit with echo-planar imaging capabilities. Carotid arterial aneurysms were surgically created in four dogs. The ability to depict, track, and position catheters, guide wires, and Guglielmi detachable coils was assessed. Catheters were first positioned with fluoroscopic guidance. Tracking and depiction were achieved with MR imaging by using commercially available catheters filled with a gadopentetate dimeglumine solution and a fast, two-dimensional, time-resolved, variable-rate k-space sampling technique.
When either a catheter or the coaxial space between a catheter and a guide wire was filled with a solution of gadopentetate dimeglumine, catheter movement was always depicted. In the animals with aneurysms, it was possible to depict movement of a catheter into and out of the aneurysm. This was achieved by superimposing reconstructed images obtained during catheter movement onto a previously acquired MR angiogram ("road map"). Prototype Guglielmi detachable coils were successfully positioned and detached. Aneurysm obliteration was monitored with the acquisition of new road map images.
The results demonstrate the feasibility of using MR imaging to guide endovascular therapeutic procedures.
评估使用磁共振（MR）成像引导和监测血管内治疗程序的可行性。
在8只犬中使用具有回波平面成像功能的1.5-T MR设备，在MR成像引导下进行血管内治疗程序。在4只犬中手术制造颈动脉动脉瘤。评估描绘、跟踪和定位导管、导丝和 Guglielmi 可脱卸弹簧圈的能力。首先在透视引导下定位导管。通过使用填充有钆喷酸葡胺溶液的市售导管和快速二维时间分辨可变速率k空间采样技术，利用MR成像实现跟踪和描绘。
当导管或导管与导丝之间的同轴空间填充有钆喷酸葡胺溶液时，总能描绘出导管的移动。在患有动脉瘤的动物中，有可能描绘出导管进出动脉瘤的移动。这是通过将导管移动过程中获得的重建图像叠加到先前获取的MR血管造影（“路线图”）上来实现的。成功定位并分离了原型 Guglielmi 可脱卸弹簧圈。通过获取新的路线图图像监测动脉瘤闭塞情况。
结果表明使用MR成像引导血管内治疗程序是可行的。
