Ritchie L D, King J C
Department of Nutritional Sciences, University of California, Berkeley 94720-3104, USA.
Am J Clin Nutr. 2000 May;71(5 Suppl):1371S-4S. doi: 10.1093/ajcn/71.5.1371s.
The evidence that calcium plays a role in the etiology, prevention, and treatment of pregnancy-induced hypertension (PIH) is reviewed. The precise factors involved in the pathogenesis of PIH are unclear, but several alterations in calcium metabolism have been identified. Epidemiologic data suggest an inverse correlation between dietary calcium intake and incidence of PIH. Although evidence suggests a possible beneficial effect of supplemental calcium, contradictions persist in clinical trials of pregnant women. Presently, there is insufficient evidence to support routine calcium supplementation of all pregnant women. However, high-risk groups, such as pregnant teens, populations with inadequate calcium intake, and women at risk of developing PIH, may benefit from consuming additional dietary calcium.
本文综述了钙在妊娠高血压综合征（PIH）的病因、预防及治疗中所起作用的证据。PIH发病机制中的确切因素尚不清楚，但已发现钙代谢存在多种改变。流行病学数据表明，膳食钙摄入量与PIH发病率呈负相关。虽然有证据表明补充钙可能有益，但孕妇临床试验中仍存在矛盾之处。目前，尚无足够证据支持对所有孕妇进行常规补钙。然而，高危人群，如青少年孕妇、钙摄入量不足人群以及有患PIH风险的女性，可能会从额外摄入膳食钙中获益。
