Pelster B
Z Parasitenkd. 1975 Dec 23;48(2):95-110. doi: 10.1007/BF00389641.
After superinfection of immunized mice with a virulent strain of Toxoplasma (BK) these mice don't die. There is formation of a cellrich exudate with only very few toxoplasmas. The number of the different exudate-cells (macrophages, big, middlesized and small lymphocytes and heterophils) turn in direction of the lymphocytes in that way, that after the 3rd day of infection 70% of all exudate-cells belong to the group of lymphocytes. They seem to cause the death of the toxoplasmas. After in vitro incubation of trophozoites and exudate-cells of immune mice for 2 hours at 37 degrees C nearly 80% of the added toxoplasmas are killed. Electronmicroscopical pictures show, that this killing is produced by a process of lysis.
用强毒株弓形虫(BK)对免疫小鼠进行重复感染后,这些小鼠不会死亡。会形成富含细胞的渗出物,其中弓形虫极少。不同渗出细胞(巨噬细胞、大、中、小淋巴细胞和嗜中性粒细胞)的数量朝着淋巴细胞的方向转变,以至于在感染第3天后,所有渗出细胞中有70%属于淋巴细胞群体。它们似乎导致了弓形虫的死亡。将免疫小鼠的滋养体和渗出细胞在37℃体外培养2小时后,近80%添加的弓形虫被杀死。电子显微镜照片显示,这种杀伤是由溶解过程产生的。