对抗结核药物的矛盾反应。
Paradoxical response to antitubercular drugs.
作者信息
Kumar S, Puri V, Mehndiratta M M, Gupta S, Bhutani A, Sharma C
机构信息
Department of Neurosurgery, Neurology and Radiology, G.B. Pant Hospital, New Delhi.
出版信息
Indian J Pediatr. 1995 Nov-Dec;62(6):695-701. doi: 10.1007/BF02825120.
Seven patients with paradoxical response to antitubercular drugs are reported. In three cases of intracranial tuberculomas, newer lesions appeared and in two cases preexisting tuberculomas enlarged. In two cases of tubercular meningitis, multiple tuberculomas appeared. All these cases exhibited newer symptoms and CT/MBI revealed the paradoxical response to antitubercular drugs. All responded to continued conservative therapy, with addition of pyrazinamide.
报告了7例对抗结核药物有矛盾反应的患者。在3例颅内结核瘤患者中，出现了新的病灶，2例既往存在的结核瘤增大。在2例结核性脑膜炎患者中，出现了多个结核瘤。所有这些病例均表现出新的症状，CT/MBI显示对抗结核药物有矛盾反应。所有患者对继续的保守治疗有效，同时加用了吡嗪酰胺。
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