Reid R, Ivey K J, Rencoret R H, Storey B
Br Med J. 1976 Apr 10;1(6014):870-2. doi: 10.1136/bmj.1.6014.870.
Among 56 pregnancies complicated by obstetric cholestasis five intrauterine deaths and one neonatal death occurred between 33 and 39 weeks, and a further six infants required urgent delivery for intrapartum asphyxia. Eighteen spontaneous premature deliveries occurred. Five mothers required specific treatment for unexplained postpartum haemorrhage. Cholestasis of pregnancy is therefore not a condition benign to the fetus, and it may contribute to increased maternal morbidity.
在56例并发产科胆汁淤积症的妊娠中,有5例胎儿宫内死亡和1例新生儿死亡发生在33至39周之间,另有6例婴儿因产时窒息需要紧急分娩。发生了18例自然早产。5名母亲因不明原因的产后出血需要特殊治疗。因此,妊娠胆汁淤积症对胎儿并非良性疾病,它可能会增加孕产妇的发病率。