Smith J B, Eaton G J
J Immunol. 1976 Jul;117(1):319-22.
A cell population recovered after velocity sedimentation fractionation of "nude" but not haired mouse spleen cells suppressed the response of spleen cells from both "nude" and haired mice to the B cell mitogen, LPS. The suppressor activity of these cells was abrogated by treatment with anti-theta antiserum and complement but not by treatment with the same antiserum preabsorbed with mouse brain. It is possible that these suppressor cells come from the pool of T cell precursors known to be present in "nude" bone marrow and spleen, and that they do not require thymic influence in order to perform the suppressor function.
经速度沉降分级分离的“裸”鼠而非有毛鼠脾细胞中恢复的细胞群体，抑制了“裸”鼠和有毛鼠脾细胞对B细胞促有丝分裂原LPS的反应。用抗θ抗血清和补体处理可消除这些细胞的抑制活性，但用经小鼠脑预先吸附的相同抗血清处理则不能。这些抑制细胞可能来自已知存在于“裸”鼠骨髓和脾脏中的T细胞前体库，并且它们执行抑制功能不需要胸腺的影响。
