与多发性骨髓瘤相关的Buschke硬肿病中皮肤扩张性的生物力学测量。

Biomechanical measurement of skin distensibility in scleredema of Buschke associated with multiple myeloma.

作者信息

Grudeva-Popova J, Dobrev H

机构信息

Department of Clinical Haematology and Department of Dermatology, Higher Medical Institute, Plovdiv, Bulgaria.

出版信息

Clin Exp Dermatol. 2000 May;25(3):247-9. doi: 10.1046/j.1365-2230.2000.00627.x.

DOI:10.1046/j.1365-2230.2000.00627.x

PMID:10844508

Abstract

We report a case of scleredema of Buschke associated with IgG kappa monoclonal hypergammaglobulinaemia. After myeloma polychemotherapy an improvement in skin involvement was observed and confirmed by means of noninvasive skin elasticity measurements. This suggests a relationship between the two diseases. The bioengineering method used can be useful for early detection and monitoring the skin involvement in patients with this disease association.

摘要

我们报告一例与IgG κ单克隆高丙种球蛋白血症相关的布希克硬皮病。多发性骨髓瘤进行多药化疗后，观察到皮肤受累情况有所改善，并通过无创皮肤弹性测量得以证实。这表明这两种疾病之间存在关联。所采用的生物工程方法有助于早期检测和监测患有这种疾病关联的患者的皮肤受累情况。